Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 5/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1141407 | 0.90 | RXRA (0.41) | RXRARXRBRXRGALDH1A1POLB | |
| SCHEMBL15266343 | 0.86 | RXRA (0.41) | RXRARXRBRXRGALDH1A1POLB | |
| SCHEMBL5413171 | 0.84 | RXRA (0.40) | RXRARXRBRXRGALDH1A1POLB | |
| SCHEMBL1142105 | 0.83 | RXRA (0.41) | RXRARXRBRXRGALDH1A1POLB | |
| SCHEMBL1141704 | 0.83 | RXRA (0.39) | RXRARXRBRXRGALDH1A1POLB | |
| SCHEMBL1141337 | 0.82 | RXRA (0.41) | RXRARXRBRXRGALDH1A1POLB | |
| SCHEMBL1141249 | 0.82 | RXRA (0.41) | RXRARXRBRXRGALDH1A1POLB | |
| SCHEMBL5418094 | 0.82 | RXRA (0.42) | RXRARXRBRXRGALDH1A1POLB | |
| SCHEMBL10263333 | 0.81 | RXRA (0.40) | RXRARXRBRXRGALDH1A1POLB | |
| SCHEMBL1141755 | 0.80 | RXRA (0.43) | RXRARXRBRXRGCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018138739-A1 | NOVEL ANTIESTROGENIC HETEROCYCLIC COMPOUNDS | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2018-08-02 | — | — | WO | disclosed |