Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25712271 | 0.79 | CYP2C9 (0.33) | CYP2C9 | |
| SCHEMBL16646886 | 0.79 | MEN1 (0.31) | CYP2C9 | |
| SCHEMBL18959027 | 0.74 | MEN1 (0.34) | — | |
| SCHEMBL18959129 | 0.71 | CYP2C9 (0.38) | CYP2C9POLB | |
| SCHEMBL24714668 | 0.68 | MEN1 (0.35) | CYP2C9POLB | |
| SCHEMBL11809406 | 0.66 | — | — | |
| SCHEMBL11809392 | 0.66 | — | — | |
| SCHEMBL11965638 | 0.66 | — | — | |
| SCHEMBL15575384 | 0.66 | KDM4E (0.30) | — | |
| SCHEMBL15575385 | 0.66 | KDM4E (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018140512-A1 | FUSED BICYCLIC BENZOHETEROAROMATIC COMPOUNDS AND METHODS OF USE THEREOF | ARAXES PHARMA LLC (US) | 2018-08-02 | — | — | WO | disclosed |
| WO-2018140514-A1 | 1-(6-(3-HYDROXYNAPHTHALEN-1-YL)QUINAZOLIN-2-YL)AZETIDIN-1-YL)PROP-2-EN-1-ONE DERIVATIVES AND SIMILAR COMPOUNDS AS KRAS G12C INHIBITORS FOR THE TREATMENT OF CANCER | ARAXES PHARMA LLC (US) | 2018-08-02 | — | — | WO | disclosed |