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SCHEMBL20439492

SCHEMBL20439492

CC(C)C(N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 15/20 0.43
▸ NPY1R P25929 9/20 0.43
▸ NPY5R Q15761 8/20 0.43
▸ NPY2R P49146 5/20 0.43
▸ NMT2 O60551 1/20 0.40
▸ NMT1 P30419 1/20 0.40
▸ NOD1 Q9Y239 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16189769 1.00 NPY4R (0.43) NPY4RNPY1RNPY5RNPY2RNMT2
SCHEMBL31590650 0.99 NPY4R (0.41) NPY4RNPY1RNPY5RNPY2RNMT2
SCHEMBL21146566 0.98 NPY4R (0.43) NPY4RNPY1RNPY5RNPY2RNMT2
SCHEMBL20439491 0.98 NPY4R (0.43) NPY4RNPY1RNPY5RNPY2RNMT2
SCHEMBL29636370 0.98 NPY4R (0.43) NPY4RNPY1RNPY5RNPY2RNMT2
SCHEMBL29434559 0.96 NPY4R (0.43) NPY4RNPY1RNPY5RNPY2RNMT2
SCHEMBL30302920 0.95 NPY4R (0.45) NPY4RNPY1RNPY5RNPY2RNOD1
SCHEMBL16189775 0.94 NMT1 (0.48) NPY4RNPY1RNPY5RNPY2RNMT2
SCHEMBL29452740 0.93 NPY4R (0.48) NPY4RNPY1RNPY5RNPY2R
SCHEMBL20439406 0.93 NPY4R (0.41) NPY4RNPY1RNPY5RNPY2RNMT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018140563-A1 USE OF APOE MIMETIC PEPTIDES FOR REDUCING THE LIKELIHOOD OF EPILEPTOGENESIS DUKE UNIVERSITY (US) 2018-08-02 — — WO disclosed
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