Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 13/20 | 0.43 |
| ▸ | NPY1R | P25929 | 7/20 | 0.43 |
| ▸ | NPY2R | P49146 | 5/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.43 |
| ▸ | NMT2 | O60551 | 1/20 | 0.41 |
| ▸ | NMT1 | P30419 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20439491 | 1.00 | NPY4R (0.43) | NPY4RNPY1RNPY2RNPY5RNMT2 | |
| SCHEMBL16189769 | 0.98 | NPY4R (0.43) | NPY4RNPY1RNPY2RNPY5RNMT2 | |
| SCHEMBL20439492 | 0.98 | NPY4R (0.43) | NPY4RNPY1RNPY2RNPY5RNMT2 | |
| SCHEMBL31590650 | 0.96 | NPY4R (0.41) | NPY4RNPY1RNPY2RNPY5RNMT2 | |
| SCHEMBL29636370 | 0.95 | NPY4R (0.43) | NPY4RNPY1RNPY2RNPY5RNMT2 | |
| SCHEMBL20439406 | 0.95 | NPY4R (0.41) | NPY4RNPY1RNPY2RNPY5RNMT2 | |
| SCHEMBL16189775 | 0.95 | NMT1 (0.48) | NPY4RNPY1RNPY2RNPY5RNMT2 | |
| SCHEMBL29434559 | 0.94 | NPY4R (0.43) | NPY4RNPY1RNPY2RNPY5RNMT2 | |
| SCHEMBL30302920 | 0.93 | NPY4R (0.45) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL20439462 | 0.92 | NPY4R (0.48) | NPY4RNPY1RNPY2RNPY5RNMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11136371-B2 | Peptide compounds for suppressing inflammation | DUKE UNIVERSITY (US) | 2021-10-05 | — | — | US | disclosed |
| US-20190194296-A1 | PEPTIDE COMPOUNDS FOR SUPPRESSING INFLAMMATION | UNIV DUKE (US) | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11136371-B2 | Peptide compounds for suppressing inflammation | APOB, IAPP, CCL2 | NPY4R 722/4885NPY1R 652/4885NPY2R 830/4885 |
| US-20190194296-A1 | PEPTIDE COMPOUNDS FOR SUPPRESSING INFLAMMATION | APOB, IAPP, CCL2 | NPY4R 722/4885NPY1R 652/4885NPY2R 830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.