Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29551120 | 1.00 | NNMT (0.50) | NNMTKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL20439711 | 0.88 | DPP4 (0.48) | NNMTMAPTFDPSCCNCCDK8 | |
| SCHEMBL29550737 | 0.88 | DPP4 (0.48) | NNMTMAPTFDPSCCNCCDK8 | |
| SCHEMBL20425589 | 0.88 | NNMT (0.54) | NNMTKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL18613639 | 0.82 | KMT2A (0.43) | NNMTKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL3931438 | 0.82 | KMT2A (0.43) | NNMTKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL18613637 | 0.82 | KMT2A (0.43) | NNMTKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL3930401 | 0.82 | KMT2A (0.43) | NNMTKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL3785658 | 0.80 | MAPT (0.46) | KMT2AALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL3785660 | 0.80 | MAPT (0.46) | KMT2AALDH1A1KDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018140876-A1 | NRF2 ACTIVATOR | BIOGEN MA INC. (US) | 2018-08-02 | — | — | WO | disclosed |