Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 15/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.44 |
| ▸ | PDE2A | O00408 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21642602 | 0.85 | BRD4 (0.51) | BRD4 | |
| SCHEMBL3326247 | 0.75 | PDE10A (0.43) | BRD4PDE10APDE2A | |
| SCHEMBL3324729 | 0.75 | PDE10A (0.45) | BRD4PDE10APDE2A | |
| SCHEMBL20440441 | 0.75 | BRD4 (0.72) | BRD4 | |
| SCHEMBL21642229 | 0.74 | BRD4 (0.81) | BRD4 | |
| SCHEMBL14764909 | 0.74 | PDE2A (0.56) | PDE10APDE2A | |
| SCHEMBL20440439 | 0.70 | BRD4 (1.00) | BRD4 | |
| SCHEMBL20440358 | 0.70 | BRD4 (1.00) | BRD4 | |
| SCHEMBL21642530 | 0.69 | BRD4 (0.49) | BRD4 | |
| SCHEMBL3324690 | 0.69 | PDE2A (0.67) | PDE10APDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018139876-A1 | NOVEL [1,2,4]TRIAZOLO[4, 3-A]QUINOXALINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING BET PROTEIN-RELATED DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT | 동화약품주식회사 | 2018-08-02 | — | — | WO | disclosed |