SCHEMBL2044082

SCHEMBL2044082

CC1COC(c2ccccc2-c2ccccc2C2=NC(C)CO2)=N1

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.54
NPC1 O15118 3/20 0.44
RAB9A P51151 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
NOS3 P29474 1/20 0.42
NOS2 P35228 1/20 0.42
OPRK1 P41145 1/20 0.37
ADRA2A P08913 1/20 0.37
ADRA2B P18089 1/20 0.37
POLB P06746 1/20 0.35
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2119357 0.98 MAPT (0.55) MAPTNPC1RAB9ASMN1; SMN2NOS3
SCHEMBL13991579 0.89 MAPT (0.49) MAPTNPC1RAB9ASMN1; SMN2NOS3
SCHEMBL17247289 0.87 MAPT (0.50) MAPTNPC1RAB9ASMN1; SMN2NOS3
SCHEMBL14648487 0.87 MAPT (0.50) MAPTNPC1RAB9ASMN1; SMN2NOS3
SCHEMBL7911819 0.87 MAPT (0.50) MAPTNPC1RAB9ASMN1; SMN2NOS3
SCHEMBL28667784 0.85 MAPT (0.49) MAPTNPC1RAB9ASMN1; SMN2NOS3
SCHEMBL28667786 0.85 MAPT (0.49) MAPTNPC1RAB9ASMN1; SMN2NOS3
SCHEMBL7386839 0.80 MAPT (0.47) MAPTNPC1RAB9ASMN1; SMN2POLB
SCHEMBL17240345 0.80 MAPT (0.45) MAPTNPC1RAB9ASMN1; SMN2NOS3
SCHEMBL21162136 0.79 MAPT (0.47) MAPTNPC1RAB9ASMN1; SMN2NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8748543-B2 Polylactic acid film TEIJIN LIMITED (JP) 2014-06-10 US disclosed
US-20140066555-A1 POLYLACTIC ACID COMPOSITION AND MOLDED ARTICLE THEREOF TEIJIN LIMITED (JP) 2014-03-06 US disclosed
EP-2698252-A1 ORIENTED LAMINATED FILM Teijin Limited (JP) 2014-02-19 EP disclosed
US-8647738-B2 Film TEIJIN LIMITED (JP) 2014-02-11 US disclosed
US-20140030499-A1 ORIENTED LAMINATED FILM TEIJIN LIMITED (JP) 2014-01-30 US disclosed
US-20110263762-A1 POLYLACTIC ACID COMPOSITION AND MOLDED ARTICLE THEREOF TEIJIN LIMITED (JP) 2011-10-27 US disclosed
US-8030382-B2 Polylactic acid composition TEIJIN LIMITED (JP) 2011-10-04 US disclosed
US-20110224342-A1 POLYLACTIC ACID FILM TEIJIN LIMITED (JP) 2011-09-15 US disclosed
EP-2351792-A1 POLYLACTIC ACID COMPOSITIONS AND MOLDED ARTICLES THEREOF Teijin Chemicals, Ltd. (JP) 2011-08-03 EP disclosed
US-20110160364-A1 RESIN COMPOSITION, MANUFACTURING METHOD THEREOF, AND MOLDED ARTICLE TEIJIN LIMITED (JP) 2011-06-30 US disclosed
US-20100182694-A1 FILM TEIJIN LIMITED (JP) 2010-07-22 US disclosed
EP-2189493-A1 FILM Teijin Limited (JP) 2010-05-26 EP disclosed
US-20100093888-A1 POLYLACTIC ACID COMPOSITION TEIJIN LIMITED (JP) 2010-04-15 US disclosed
EP-2116576-A1 POLYLACTIC ACID COMPOSITION Teijin Limited (JP) 2009-11-11 EP disclosed
EP-2053091-A1 RESIN COMPOSITION, METHOD FOR PRODUCING THE SAME AND MOLDED ARTICLE TEIJIN LIMITED (JP) 2009-04-29 EP disclosed
EP-0737231-B2 THERMAL STABILIZED RESIN COMPOSITIONS KOLON INC (KR) 2005-11-02 EP disclosed
EP-0737231-B1 THERMAL STABILIZED RESIN COMPOSITIONS KOLON INC (KR) 2000-03-08 EP disclosed
US-5849820-A Thermal stabilized resin compositions KOLON INDUSTRIES, INC. (KR) 1998-12-15 US disclosed
EP-0737231-A1 THERMAL STABILIZED RESIN COMPOSITIONS KOLON INDUSTRIES, INC. (KR) 1996-10-16 EP disclosed
WO-1995018181-A1 THERMAL STABILIZED RESIN COMPOSITIONS KOLON INDUSTRIES, INC. (KR) 1995-07-06 WO disclosed