Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17247289 | 1.00 | MAPT (0.50) | MAPTNPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL2119357 | 0.89 | MAPT (0.55) | MAPTNPC1RAB9ASMN1; SMN2NOS3 | |
| SCHEMBL2044082 | 0.87 | MAPT (0.54) | MAPTNPC1RAB9ASMN1; SMN2NOS3 | |
| SCHEMBL7911819 | 0.82 | MAPT (0.50) | MAPTNPC1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL28667784 | 0.81 | MAPT (0.49) | MAPTNPC1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL28667786 | 0.81 | MAPT (0.49) | MAPTNPC1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL13991579 | 0.81 | MAPT (0.49) | MAPTNPC1RAB9ASMN1; SMN2NOS3 | |
| SCHEMBL15883113 | 0.78 | NPC1 (0.67) | MAPTNPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL12017252 | 0.78 | RAB9A (0.38) | MAPTNPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL14877791 | 0.78 | NPC1 (0.67) | MAPTNPC1RAB9ASMN1; SMN2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8653307-B2 | Liphagal enantiomers and their derivatives and precursors, and enantioselective methods of making the same | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-02-18 | — | — | US | disclosed |
| US-20130023676-A1 | LIPHAGAL ENANTIOMERS AND THEIR DERIVATIVES AND PRECURSORS, AND ENANTIOSELECTIVE METHODS OF MAKING THE SAME | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2013-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130023676-A1 | LIPHAGAL ENANTIOMERS AND THEIR DERIVATIVES AND PRECURSORS, AND ENANTIOSELECTIVE METHODS OF MAKING THE SAME | LIPC, LIPE, LIPA | MAPT 4788/4885NPC1 738/4885RAB9A 1884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.