SCHEMBL20440935

SCHEMBL20440935

COc1cccc(OC)c1C1=CC=CC1[Hf](=C(c1ccccc1)c1ccccc1)C1c2cc(C(C)(C)C)ccc2-c2ccc(C(C)(C)C)cc21

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 3/20 0.33
MRGPRX4 Q96LA9 2/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
STK10 O94804 1/20 0.30
SLK Q9H2G2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20440991 0.90 CNR1 (0.34) MRGPRX4
SCHEMBL20440938 0.87 MRGPRX4 (0.33) MRGPRX4
SCHEMBL20440949 0.87 TP53 (0.34) MEN1KMT2A
SCHEMBL20440922 0.85 AKR1C3 (0.33)
SCHEMBL20440977 0.83 RXRA (0.36)
SCHEMBL20440957 0.82
SCHEMBL20440917 0.82 RXRA (0.33)
SCHEMBL20440986 0.81 CNR1 (0.32)
SCHEMBL20440992 0.80 CNR1 (0.32)
SCHEMBL20440997 0.80 APP (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10040883-B2 Multimodal polyolefin resin and molded product prepared therefrom DAELIM INDUSTRIAL CO., LTD. (KR) 2018-08-07 US disclosed