⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29566379 | 0.95 | — | — | |
| Iodide SCHEMBL1960465 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL1361615 | 0.90 | — | — | |
| SCHEMBL2020539 | 0.90 | — | — | |
| SCHEMBL3836952 | 0.57 | — | — | |
| SCHEMBL45125 | 0.56 | — | — | |
| SCHEMBL28095 | 0.56 | — | — | |
| SCHEMBL1296 | 0.56 | — | — | |
| SCHEMBL10940023 | 0.56 | — | — | |
| SCHEMBL7240952 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273802-B2 | Silicones formed from an oxygen permeable component and a vinyl carbonate, carbamate ester or amide beta-substituted vinyl pyrrolidone; improve wettability of the lens without a surface treatment | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2012-09-25 | — | — | US | disclosed |
| US-7956131-B2 | Lactam polymer derivatives | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2011-06-07 | — | — | US | disclosed |
| US-20100171923-A1 | LACTAM POLYMER DERIVATIVES | JOHSNON & JOHNSON VISION CARE, INC. | 2010-07-08 | — | — | US | disclosed |
| US-7473738-B2 | Lactam polymer derivatives | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2009-01-06 | — | — | US | disclosed |
| US-20080275156-A1 | WETTABLE HYDROGELS COMPRISING REACTIVE, HYDROPHILIC, POLYMERIC INTERNAL WETTING AGENTS | JOHNSON & JOHNSON VISION CARE, INC. | 2008-11-06 | — | — | US | disclosed |
| EP-1800150-B1 | WETTABLE HYDROGELS COMPRISING REACTIVE, HYDROPHILIC, POLYMERIC INTERNAL WETTING AGENTS | JOHNSON & JOHNSON VISION CARE (US) | 2008-08-06 | — | — | EP | disclosed |
| US-20070290174-A1 | LACTAM POLYMER DERIVATIVES | JOHNSON & JOHNSON VISION CARE, INC. | 2007-12-20 | — | — | US | disclosed |
| US-7249848-B2 | Wettable hydrogels comprising reactive, hydrophilic, polymeric internal wetting agents | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2007-07-31 | — | — | US | disclosed |
| EP-1800150-A1 | WETTABLE HYDROGELS COMPRISING REACTIVE, HYDROPHILIC, POLYMERIC INTERNAL WETTING AGENTS | Johnson & Johnson Vision Care, Inc. (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1799724-A2 | LACTAM POLYMER DERIVATIVES | Johnson and Johnson Vision Care, Inc. (US) | 2007-06-27 | — | — | EP | disclosed |
| US-7195882-B2 | Monoclonal antibodies specific for buprenorphine and metabolites thereof | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2007-03-27 | — | — | US | disclosed |
| WO-2006039466-A1 | WETTABLE HYDROGELS COMPRISING REACTIVE, HYDROPHILIC, POLYMERIC INTERNAL WETTING AGENTS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2006-04-13 | — | — | WO | disclosed |
| WO-2006039276-A2 | LACTAM POLYMER DERIVATIVES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2006-04-13 | — | — | WO | disclosed |
| US-20060072069-A1 | Wettable hydrogels comprising reactive, hydrophilic, polymeric internal wetting agents | JOHNSON & JOHNSON VISION CARE, INC. | 2006-04-06 | — | — | US | disclosed |
| US-20060069235-A1 | Lactam polymer derivatives | JOHNSON & JOHNSON VISION CARE, INC. | 2006-03-30 | — | — | US | disclosed |
| EP-1633788-A2 | MONOCLONAL ANTIBODIES SPECIFIC FOR BUPRENORPHINE AND METABOLITES THEREOF | Roche Diagnostics GmbH (DE) | 2006-03-15 | — | — | EP | disclosed |
| US-20040248222-A1 | Monoclonal antibodies specific for buprenorphine and metabolites thereof | ROCHE DIAGNOSTICS CORPORATION | 2004-12-09 | — | — | US | disclosed |
| WO-2004106385-A2 | MONOCLONAL ANTIBODIES SPECIFIC FOR BUPRENORPHINE AND METABOLITES THEREOF | ROCHE DIAGNOSTICS GMBH (DE) | 2004-12-09 | — | — | WO | disclosed |