Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
| ▸ | MAOA | P21397 | 4/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | PTGIR | P43119 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | FURIN | P09958 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438185 | 0.91 | PARP10 (0.47) | MAOBMAOAPARP10HPGDALDH1A1 | |
| SCHEMBL18058688 | 0.82 | SMN1; SMN2 (0.54) | PARP10HPGDALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL943014 | 0.82 | PARP10 (0.46) | PARP10HPGDALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL2242868 | 0.82 | PARP10 (0.55) | PARP10HPGDALDH1A1TSHRHRH3 | |
| SCHEMBL3457580 | 0.80 | PARP10 (0.47) | PARP10HPGDALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL23323067 | 0.76 | MAOA (0.53) | MAOBMAOAALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL23295277 | 0.75 | MAOA (0.65) | MAOBMAOAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL16195543 | 0.74 | SMN1; SMN2 (0.67) | PARP10HPGDALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL623629 | 0.74 | PARP10 (0.53) | PARP10HPGDALDH1A1TSHRHRH3 | |
| SCHEMBL26012610 | 0.74 | PARP10 (0.53) | PARP10HPGDALDH1A1TSHRHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018137655-A1 | PYRROLO-PYRIDINES N-OXIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 江苏豪森药业集团有限公司 | 2018-08-02 | — | — | WO | disclosed |