Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 20/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 8/20 | 0.39 |
| ▸ | CCR2 | P41597 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20443493 | 0.83 | KRAS (0.46) | — | |
| SCHEMBL29447726 | 0.83 | KRAS (0.46) | — | |
| SCHEMBL20443494 | 0.79 | KRAS (0.49) | — | |
| SCHEMBL29447729 | 0.79 | KRAS (0.49) | — | |
| SCHEMBL29447722 | 0.77 | KRAS (0.51) | — | |
| SCHEMBL20443590 | 0.77 | KRAS (0.51) | — | |
| SCHEMBL29447768 | 0.70 | KRAS (0.47) | — | |
| SCHEMBL20443594 | 0.70 | KRAS (0.47) | — | |
| SCHEMBL29447689 | 0.66 | KRAS (0.50) | — | |
| SCHEMBL20443592 | 0.66 | KRAS (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018140512-A1 | FUSED BICYCLIC BENZOHETEROAROMATIC COMPOUNDS AND METHODS OF USE THEREOF | ARAXES PHARMA LLC (US) | 2018-08-02 | — | — | WO | disclosed |