SCHEMBL2044441

SCHEMBL2044441

CCCC(C(=O)O)C1CNCCN1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPN1 P15169 2/20 0.37
CPB2 Q96IY4 2/20 0.37
CHRM1 P11229 1/20 0.35
AKR1A1 P14550 1/20 0.35
CHRM3 P20309 1/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
ADRA1A P35348 1/20 0.35
HRH1 P35367 1/20 0.35
DRD3 P35462 1/20 0.35
SLC6A3 Q01959 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CPA1 P15085 1/20 0.32
SLC6A1 P30531 2/20 0.30
GABRA5 P31644 2/20 0.30
GABRB2 P47870 2/20 0.30
SLC6A12 P48065 2/20 0.30
SLC6A11 P48066 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3986419 0.86 CPN1 (0.39) CPN1CPB2CPA1SLC6A1GABRA5
SCHEMBL28011821 0.85 CHRM1 (0.36) CPN1CPB2CHRM1AKR1A1CHRM3
SCHEMBL4002689 0.73 CPN1 (0.32) CPN1CPB2SLC6A1GABRA5GABRB2
SCHEMBL27772878 0.71 SLC6A1 (0.32) SLC6A1GABRA5GABRB2SLC6A12SLC6A11
SCHEMBL28301971 0.70 CPN1 (0.62) CPN1CPB2CHRM1AKR1A1CHRM3
SCHEMBL3102774 0.70
Hydrochloric Acid SCHEMBL17111214 0.70 SLC6A2 (0.37) CPN1CPB2CHRM1AKR1A1CHRM3
SCHEMBL28069380 0.69 FFAR1 (0.45)
SCHEMBL7768091 0.69 ITGB1 (0.40) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL11721760 0.68 SLC6A2 (0.34) SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2331139-A2 POLYMERIC ALPHA-HYDROXY ALDEHYDE AND KETONE REAGENTS AND CONJUGATION METHOD Nektar Therapeutics (US) 2011-06-15 EP disclosed
WO-2010030366-A2 POLYMERIC ALPHA-HYDROXY ALDEHYDE AND KETONE REAGENTS AND CONJUGATION METHOD NEKTAR THERAPEUTICS (US) 2010-03-18 WO disclosed