Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20444567 | 0.84 | GAA (0.33) | SMN1; SMN2GAAAKT1 | |
| SCHEMBL29843848 | 0.76 | KMT2A (0.42) | MAPTMAPK1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL20424965 | 0.76 | KMT2A (0.42) | MAPTMAPK1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL20444336 | 0.70 | ALDH1A1 (0.39) | PDPK1MAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL20444571 | 0.68 | KDM4E (0.38) | MAPTMAPK1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL22335167 | 0.66 | PDPK1 (0.41) | PDPK1MAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24891144 | 0.65 | ELANE (0.44) | PDPK1ALDH1A1 | |
| SCHEMBL22342563 | 0.65 | PARP1 (0.44) | PDPK1MAPTALDH1A1NCF1 | |
| SCHEMBL20444679 | 0.65 | PDPK1 (0.47) | PDPK1MAPTMAPK1ALDH1A1KDM4E | |
| SCHEMBL20444686 | 0.65 | PDPK1 (0.39) | PDPK1MAPTALDH1A1NCF1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3573985-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2023-01-18 | — | — | EP | disclosed |
| WO-2018138306-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-08-02 | — | — | WO | disclosed |