Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 6/20 | 0.72 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.62 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.59 |
| ▸ | GUSB | P08236 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | MGAM | O43451 | 1/20 | 0.57 |
| ▸ | SI | P14410 | 1/20 | 0.57 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23736189 | 0.99 | SMPD3 (0.70) | SMPD3NOX1CYP1A1CYP1B1GUSB | |
| SCHEMBL27662258 | 0.88 | SMPD3 (0.73) | SMPD3NOX1GUSBMAPTMEN1 | |
| SCHEMBL8088592 | 0.87 | NOX1 (0.81) | SMPD3NOX1CYP1A1CYP1B1GUSB | |
| SCHEMBL18292680 | 0.78 | NOX1 (0.78) | SMPD3NOX1MAPTMEN1KMT2A | |
| SCHEMBL7143433 | 0.77 | MAPT (0.64) | SMPD3NOX1GUSBMAPTMEN1 | |
| SCHEMBL31305589 | 0.76 | NPY5R (0.68) | SMPD3NOX1MEN1KMT2AGAA | |
| SCHEMBL20445309 | 0.76 | SMPD3 (0.61) | SMPD3NOX1GUSBMAPTMEN1 | |
| SCHEMBL724250 | 0.76 | NPY5R (0.72) | SMPD3NOX1MAPTMEN1KMT2A | |
| SCHEMBL9425243 | 0.76 | NOX1 (0.58) | SMPD3NOX1CYP1A1CYP1B1CYP1A2 | |
| SCHEMBL5131089 | 0.76 | SMPD3 (0.56) | SMPD3NOX1MAPTTP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3573957-B1 | COMPOSITIONS AND METHODS FOR BLOCKING SODIUM CHANNELS | RIVARA MIRKO (IT) | 2023-04-26 | — | — | EP | disclosed |
| US-11090289-B2 | Compositions and methods for blocking sodium channels | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2021-08-17 | — | — | US | disclosed |
| WO-2018140504-A1 | COMPOSITIONS AND METHODS FOR BLOCKING SODIUM CHANNELS | PATEL MANOJ K (US) | 2018-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11090289-B2 | Compositions and methods for blocking sodium channels | SCN3A, SCN1B, SCN2B | SMPD3 203/4885NOX1 1365/4885CYP1A1 2779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.