Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 5/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.43 |
| ▸ | ESRRB | O95718 | 1/20 | 0.41 |
| ▸ | ESRRA | P11474 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HNF4A | P41235 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15789381 | 0.85 | ESR1 (0.45) | ESR1ESR2CYP1A2MEN1KMT2A | |
| SCHEMBL24755265 | 0.80 | ESR1 (0.46) | ESR1ESR2CYP1A2KCNJ11 | |
| SCHEMBL29678582 | 0.80 | ESR1 (0.46) | ESR1ESR2CYP1A2KCNJ11 | |
| SCHEMBL29679858 | 0.80 | ESR1 (0.46) | ESR1ESR2CYP1A2KCNJ11 | |
| SCHEMBL2128646 | 0.80 | CA12 (0.46) | POLBALOX5TSHR | |
| Hydrochloric Acid SCHEMBL29975430 | 0.79 | ESR1 (0.44) | ESR1ESR2CYP1A2KCNJ11 | |
| Hydrochloric Acid SCHEMBL30487944 | 0.79 | ESR1 (0.44) | ESR1ESR2CYP1A2KCNJ11 | |
| SCHEMBL2050978 | 0.79 | TYR (0.47) | HSD17B3ESR1ESR2TYRMEN1 | |
| SCHEMBL22539300 | 0.78 | — | — | |
| SCHEMBL2455631 | 0.77 | ESR1 (0.44) | HSD17B3ESR1ESR2ESRRBESRRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8344080-B2 | Catalyst for olefin polymerization and method of preparation thereof | WANG LICAI (CN) | 2013-01-01 | — | — | US | disclosed |
| US-20110301385-A1 | CATALYST FOR OLEFIN POLYMERIZATION AND METHOD OF PREPARATION THEREOF | WANG LICAI (CN) | 2011-12-08 | — | — | US | disclosed |
| US-7964678-B2 | Comprises titanium/magnesium-1,4-diether [2,2'-dialkoxy-1,1'-biphenyl, 2,2'-dialkoxy-1,1'-binaphthalene, 10,10'-dialkoxy-9,9-biphenanthrene complex, organoaluminum compound, and organosilicon compound; molecular weight control | WANG LICAI | 2011-06-21 | — | — | US | disclosed |
| US-20080161513-A1 | Catalyst for Olefin Polymerization and Preparation Thereof and Polymerization Process | YINGKOU XIANGYANG CATALYST CO., LTD. (CN) | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301385-A1 | CATALYST FOR OLEFIN POLYMERIZATION AND METHOD OF PREPARATION THEREOF | PPOX, CAT, POR | HSD17B3 1318/4885ESR1 2315/4885ESR2 3033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.