SCHEMBL2044635

SCHEMBL2044635

N#Cc1[nH]c2ccccc2c1C=CC(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.48
MEN1 O00255 7/20 0.48
KMT2A Q03164 7/20 0.48
ALDH1A1 P00352 5/20 0.48
LMNA P02545 2/20 0.48
HPGD P15428 2/20 0.41
PSMD14 O00487 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KDM4E B2RXH2 3/20 0.40
HDAC3 O15379 1/20 0.40
TNKS O95271 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HCAR2 Q8TDS4 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
TNKS2 Q9H2K2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28378460 1.00 MAPT (0.48) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL22118368 0.80 MEN1 (0.49) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL27386818 0.78 MEN1 (0.52) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL29955048 0.78 AHR (0.48) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL25334743 0.77 MAPT (0.51) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL29033517 0.77 MEN1 (0.63) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL25922845 0.77 MAPT (0.51) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL18919149 0.77 MEN1 (0.76) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL18919152 0.77 MEN1 (0.76) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL8804361 0.75 KMT2A (0.48) MAPTMEN1KMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2328938-A1 RADICALLY FUNCTIONALIZED OLEFIN-BASED POLYMER WITH REDUCED MOLECULAR WEIGHT CHANGE AND METHOD Dow Global Technologies LLC (US) 2011-06-08 EP claimed
WO-2010036642-A1 RADICALLY FUNCTIONALIZED OLEFIN-BASED POLYMER WITH REDUCED MOLECULAR WEIGHT CHANGE AND METHOD DOW GLOBAL TECHNOLOGIES INC. (US) 2010-04-01 WO claimed
EP-2328938-A1 RADICALLY FUNCTIONALIZED OLEFIN-BASED POLYMER WITH REDUCED MOLECULAR WEIGHT CHANGE AND METHOD Dow Global Technologies LLC (US) 2011-06-08 EP disclosed
EP-2326169-A2 SUSPENSION CONCENTRATES IN OIL OF SULFONYLUREAS AND COMBINATIONS WITH FLUROXYPYR OR OTHER AGROCHEMICALS GAT Microencapsulation AG (AT) 2011-06-01 EP disclosed
WO-2010036642-A1 RADICALLY FUNCTIONALIZED OLEFIN-BASED POLYMER WITH REDUCED MOLECULAR WEIGHT CHANGE AND METHOD DOW GLOBAL TECHNOLOGIES INC. (US) 2010-04-01 WO disclosed