Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PDE9A | O76083 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5635075 | 0.78 | AHR (0.41) | AHRMEN1MAPTKMT2AKIF11 | |
| SCHEMBL2044635 | 0.78 | MAPT (0.48) | MEN1MAPTKMT2AKDM4EPDE9A | |
| SCHEMBL28378460 | 0.78 | MAPT (0.48) | MEN1MAPTKMT2AKDM4EPDE9A | |
| SCHEMBL14519076 | 0.77 | GSK3B (0.53) | AHRMEN1MAPTKMT2AKIF11 | |
| SCHEMBL7493848 | 0.76 | AHR (0.52) | AHRMEN1MAPTKMT2AKIF11 | |
| SCHEMBL5635129 | 0.76 | DRD2 (0.48) | AHRMEN1MAPTKMT2AKDM4E | |
| SCHEMBL28136136 | 0.73 | AHR (0.49) | AHRMEN1MAPTKMT2AKIF11 | |
| SCHEMBL29635217 | 0.73 | PDE9A (0.49) | AHRMEN1MAPTKMT2AKDM4E | |
| SCHEMBL2464667 | 0.73 | PDE9A (0.49) | AHRMEN1MAPTKMT2AKDM4E | |
| SCHEMBL2907190 | 0.72 | AHR (0.47) | AHRMEN1MAPTKMT2AKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |