Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 8/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20446588 | 0.89 | KLKB1 (0.37) | CTSCKLKB1PARP1RPS6KB1 | |
| SCHEMBL20446587 | 0.87 | KLKB1 (0.45) | CTSCKLKB1PARP1 | |
| SCHEMBL20446530 | 0.86 | KLKB1 (0.38) | CTSCKLKB1PARP1 | |
| SCHEMBL20446525 | 0.86 | CTSC (0.34) | CTSCKLKB1IDH1 | |
| SCHEMBL20446515 | 0.82 | KLKB1 (0.46) | KLKB1 | |
| SCHEMBL20446512 | 0.81 | KLKB1 (0.35) | KLKB1 | |
| SCHEMBL20584260 | 0.81 | KLKB1 (0.53) | KLKB1 | |
| SCHEMBL29581504 | 0.81 | KLKB1 (0.53) | KLKB1 | |
| SCHEMBL20446522 | 0.80 | KLKB1 (0.38) | KLKB1 | |
| SCHEMBL20446554 | 0.79 | KLKB1 (0.44) | KLKB1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3355890-A1 | HUMAN PLASMA KALLIKREIN INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2018-08-08 | — | — | EP | disclosed |