Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 13/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17064730 | 0.88 | GAA (0.35) | GAAPARP1LMNATSHRCHRM3 | |
| SCHEMBL20446610 | 0.82 | CYP4F2 (0.35) | TSHR | |
| SCHEMBL17064970 | 0.80 | RAB9A (0.37) | GAAPARP1CHRM3GLA | |
| SCHEMBL20446520 | 0.79 | DPP4 (0.37) | GAACHRM3GLA | |
| SCHEMBL17064821 | 0.79 | RAB9A (0.39) | GAAPARP1CHRM3GLA | |
| SCHEMBL17064479 | 0.79 | DPP4 (0.37) | GAACHRM3GLA | |
| SCHEMBL17064440 | 0.77 | GAA (0.37) | GAAPARP1LMNATSHRGLA | |
| SCHEMBL17064939 | 0.75 | KLKB1 (0.52) | CHRM3KLKB1 | |
| SCHEMBL20446561 | 0.70 | CYP4F2 (0.33) | TSHR | |
| SCHEMBL20446536 | 0.70 | KLKB1 (0.38) | GAAPARP1LMNAKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3355890-A1 | HUMAN PLASMA KALLIKREIN INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2018-08-08 | — | — | EP | disclosed |