Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | POLB | P06746 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.71 |
| ▸ | BLM | P54132 | 2/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.70 |
| ▸ | ATM | Q13315 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | NAMPT | P43490 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.60 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1499569 | 0.92 | TDP1 (0.92) | TDP1KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL5583042 | 0.86 | TDP1 (0.81) | TDP1KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL14831012 | 0.83 | ALDH1A1 (0.79) | TDP1KMT2AMEN1POLBALDH1A1 | |
| Acecainide SCHEMBL156943 | 0.83 | ALDH1A1 (1.00) | TDP1KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL12766989 | 0.83 | POLB (0.73) | TDP1KMT2AMEN1POLBALDH1A1 | |
| Acecainide SCHEMBL122991 | 0.82 | POLB (1.00) | TDP1KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL1230694 | 0.82 | ALDH1A1 (0.77) | TDP1KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL542239 | 0.81 | TDP1 (0.74) | TDP1KMT2AMEN1POLBALDH1A1 | |
| Acecainide SCHEMBL1650222 | 0.81 | ALDH1A1 (0.94) | TDP1KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL19354778 | 0.81 | NPC1 (0.59) | TDP1KMT2AMEN1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10619028-B2 | Polyarylene fiber with improved hydrolytic stability | TEIJIN ARAMID B.V. (NL) | 2020-04-14 | — | — | US | disclosed |
| EP-3356585-B1 | POLYARYLENE FIBER WITH IMPROVED HYDROLYTIC STABILITY | TEIJIN ARAMID BV (NL) | 2019-05-15 | — | — | EP | disclosed |
| US-20180223077-A1 | POLYARYLENE FIBER WITH IMPROVED HYDROLYTIC STABILITY | TEIJIN ARAMID B.V. (NL) | 2018-08-09 | — | — | US | disclosed |
| EP-3356585-A1 | POLYARYLENE FIBER WITH IMPROVED HYDROLYTIC STABILITY | Teijin Aramid B.V. (NL) | 2018-08-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10619028-B2 | Polyarylene fiber with improved hydrolytic stability | PAH, COMT, MAOB | TDP1 96/4885KMT2A 2022/4885MEN1 4105/4885 |
| US-20180223077-A1 | POLYARYLENE FIBER WITH IMPROVED HYDROLYTIC STABILITY | PAH, COMT, DBH | TDP1 94/4885KMT2A 2313/4885MEN1 4226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.