Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC1R | Q01726 | 9/20 | 0.65 |
| ▸ | MC4R | P32245 | 9/20 | 0.65 |
| ▸ | MC5R | P33032 | 1/20 | 0.38 |
| ▸ | MC3R | P41968 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1310203 | 1.00 | MC1R (0.65) | MC1RMC4RMC5RMC3RITGB3 | |
| SCHEMBL1310622 | 0.93 | MC1R (0.65) | MC1RMC4RMC5RMC3RITGB3 | |
| SCHEMBL1325753 | 0.93 | MC1R (0.64) | MC1RMC4RMC5RMC3RITGB3 | |
| SCHEMBL1324983 | 0.92 | MC1R (0.64) | MC1RMC4RMC5RMC3RITGB3 | |
| SCHEMBL15273371 | 0.91 | MC1R (0.62) | MC1RMC4RMC5RMC3RITGB3 | |
| SCHEMBL2154492 | 0.90 | MC1R (0.70) | MC1RMC4RMC5RMC3RP2RY12 | |
| SCHEMBL20450360 | 0.87 | MC1R (0.78) | MC1RMC4RMC5RMC3RITGB3 | |
| SCHEMBL1310839 | 0.87 | MC1R (0.78) | MC1RMC4RMC5RMC3RITGB3 | |
| SCHEMBL1310201 | 0.87 | MC1R (0.78) | MC1RMC4RMC5RMC3RITGB3 | |
| SCHEMBL1310458 | 0.86 | MC1R (0.76) | MC1RMC4RMC5RMC3RITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342194-B1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2018-08-08 | — | — | EP | claimed |