Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC1R | Q01726 | 9/20 | 0.52 |
| ▸ | MC4R | P32245 | 8/20 | 0.52 |
| ▸ | MC5R | P33032 | 1/20 | 0.44 |
| ▸ | MC3R | P41968 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.35 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1312766 | 1.00 | MC1R (0.52) | MC1RMC4RMC5RMC3RPTPN1 | |
| Butyramide SCHEMBL2153673 | 0.96 | MC1R (0.48) | MC1RMC4RMC5RMC3RPTPN1 | |
| SCHEMBL1310614 | 0.90 | MC1R (0.53) | MC1RMC4RMC5RMC3RPTPN1 | |
| SCHEMBL20450380 | 0.90 | MC1R (0.53) | MC1RMC4RMC5RMC3RPTPN1 | |
| SCHEMBL20450397 | 0.89 | MC1R (0.55) | MC1RMC4RMC5RMC3RPTPN1 | |
| SCHEMBL2153417 | 0.87 | MC1R (0.53) | MC1RMC4RMC5RMC3RITGB3 | |
| SCHEMBL20450418 | 0.86 | MC1R (0.53) | MC1RMC4RMC5RMC3RITGB3 | |
| SCHEMBL1311171 | 0.86 | MC1R (0.53) | MC1RMC4RMC5RMC3RITGB3 | |
| SCHEMBL20450374 | 0.86 | MC1R (0.65) | MC1RMC4RMC5RMC3RITGB3 | |
| SCHEMBL1313377 | 0.86 | MC1R (0.65) | MC1RMC4RMC5RMC3RITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342194-B1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2018-08-08 | — | — | EP | claimed |