Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC1R | Q01726 | 9/20 | 0.55 |
| ▸ | MC4R | P32245 | 9/20 | 0.55 |
| ▸ | MC5R | P33032 | 1/20 | 0.37 |
| ▸ | MC3R | P41968 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.32 |
| ▸ | MMP9 | P14780 | 4/20 | 0.32 |
| ▸ | MMP3 | P08254 | 3/20 | 0.32 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20450445 | 0.89 | MC1R (0.52) | MC1RMC4RMC5RMC3RPTPN1 | |
| SCHEMBL1312766 | 0.89 | MC1R (0.52) | MC1RMC4RMC5RMC3RPTPN1 | |
| SCHEMBL1310622 | 0.88 | MC1R (0.65) | MC1RMC4RMC5RMC3RITGB3 | |
| Butyramide SCHEMBL2153673 | 0.85 | MC1R (0.48) | MC1RMC4RMC5RMC3RPTPN1 | |
| SCHEMBL20450421 | 0.83 | MC1R (0.64) | MC1RMC4RMC5RMC3RPTPN1 | |
| SCHEMBL1312150 | 0.83 | MC1R (0.64) | MC1RMC4RMC5RMC3RPTPN1 | |
| SCHEMBL1324983 | 0.82 | MC1R (0.64) | MC1RMC4RMC5RMC3RPTPN1 | |
| SCHEMBL1310203 | 0.82 | MC1R (0.65) | MC1RMC4RMC5RMC3RITGB3 | |
| SCHEMBL20450424 | 0.82 | MC1R (0.65) | MC1RMC4RMC5RMC3RITGB3 | |
| SCHEMBL1325753 | 0.81 | MC1R (0.64) | MC1RMC4RMC5RMC3RPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342194-B1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2018-08-08 | — | — | EP | disclosed |