Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Desmopressin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A known ✓ | P37288 | 6/20 | 0.82 |
| ▸ | AVPR2 known ✓ | P30518 | 4/20 | 0.82 |
| ▸ | AVPR1B known ✓ | P47901 | 4/20 | 0.82 |
| ▸ | OXTR | P30559 | 9/20 | 0.82 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.82 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.69 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.69 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Desmopressin SCHEMBL29354819 | 1.00 | OXTR (0.82) | OXTRAVPR1AAVPR2AVPR1BPTGS1 | |
| Desmopressin SCHEMBL6021294 | 1.00 | OXTR (0.82) | OXTRAVPR1AAVPR2AVPR1BPTGS1 | |
| Desmopressin SCHEMBL347838 | 0.99 | OXTR (0.81) | OXTRAVPR1AAVPR2AVPR1BPTGS1 | |
| Desmopressin SCHEMBL28142694 | 0.99 | OXTR (0.81) | OXTRAVPR1AAVPR2AVPR1BPTGS1 | |
| Desmopressin SCHEMBL4642385 | 0.99 | OXTR (0.81) | OXTRAVPR1AAVPR2AVPR1BPTGS1 | |
| SCHEMBL23382246 | 0.98 | OXTR (0.85) | OXTRAVPR1AAVPR2AVPR1BPTGS1 | |
| Desmopressin SCHEMBL15933169 | 0.98 | OXTR (0.85) | OXTRAVPR1AAVPR2AVPR1BPTGS1 | |
| Desmopressin SCHEMBL2687079 | 0.98 | OXTR (0.85) | OXTRAVPR1AAVPR2AVPR1BPTGS1 | |
| Desmopressin SCHEMBL21131126 | 0.98 | OXTR (0.85) | OXTRAVPR1AAVPR2AVPR1BPTGS1 | |
| Desmopressin SCHEMBL10053268 | 0.98 | OXTR (0.85) | OXTRAVPR1AAVPR2AVPR1BPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3692 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260076872-A1 | POLYMER VIALS WITH SUBSTANTIALLY FLAT BOTTOMS AND INJECTION STRETCH BLOW MOLDING METHODS FOR MAKING THE SAME | SIO2 MEDICAL PRODUCTS LLC (US) | 2026-03-19 | — | — | US | claimed |
| US-12576125-B2 | Desmopressin oral compositions | TULEX PHARMACEUTICALS INC. (US) | 2026-03-17 | — | — | US | claimed |
| EP-4687859-A2 | DESMOPRESSIN ORAL COMPOSITIONS | TULEX PHARMACEUTICALS, INC. (US) | 2026-02-11 | — | — | EP | claimed |
| US-12534571-B2 | Amphiphilic block copolymer, preparation method thereof and nanomicelle drug-loading system | SHANGHAI BEST-LINK BIOSCIENCE, LLC (CN) | 2026-01-27 | — | — | US | claimed |
| US-20250281567-A1 | DESMOPRESSIN ORAL COMPOSITIONS | TULEX PHARMACEUTICALS INC. | 2025-09-11 | — | — | US | claimed |
| EP-4603095-A2 | IMPROVED PHARMACEUTICAL FORMULATIONS | Ferring B.V. (NL) | 2025-08-20 | — | — | EP | claimed |
| US-20250242092-A1 | SiOx BARRIER FOR PHARMACEUTICAL PACKAGE AND COATING PROCESS | SIO2 MEDICAL PRODUCTS INC (US) | 2025-07-31 | — | — | US | claimed |
| EP-4577186-A1 | HAEMORRHAGE INHIBITING COMPOSITIONS AND METHODS INVOLVING THE SAME | Stellaris Pharmaceuticals ApS (DK) | 2025-07-02 | — | — | EP | claimed |
| US-12343372-B2 | Desmopressin oral compositions | TULEX PHARMACEUTICALS INC. (US) | 2025-07-01 | — | — | US | claimed |
| EP-3787596-B1 | IMPROVED PHARMACEUTICAL FORMULATIONS | FERRING BV (NL) | 2025-06-25 | — | — | EP | claimed |
| EP-0668926-A1 | MULTIPLE COAGULATION TEST DEVICE AND METHOD | GOLDSTEIN, Sheldon (US) | 1995-08-30 | — | — | EP | claimed |
| WO-1995001185-A1 | STABILIZED PHARMACEUTICAL PEPTIDE COMPOSITIONS | FERRING B.V. (NL) | 1995-01-12 | — | — | WO | claimed |
| US-5366869-A | Multiple coagulation test device and method | COAGULATION SCIENCES LLC | 1994-11-22 | — | — | US | claimed |
| WO-1994011527-A1 | MULTIPLE COAGULATION TEST DEVICE AND METHOD | GOLDSTEIN SHELDON (US) | 1994-05-26 | — | — | WO | claimed |
| US-5288498-A | Compositions of oral nondissolvable matrixes for transmucosal administration of medicaments | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 1994-02-22 | — | — | US | claimed |
| US-5288497-A | Compositions of oral dissolvable medicaments | THE UNIVERSITY OF UTAH (US) | 1994-02-22 | — | — | US | claimed |
| EP-0487520-A4 | COMPRESSED POWDER MEDICAMENTS | — | 1992-08-12 | — | — | EP | claimed |
| US-5132114-A | Compositions and methods of manufacture of compressed powder medicaments | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 1992-07-21 | — | — | US | claimed |
| EP-0487520-A1 | COMPRESSED POWDER MEDICAMENTS. | ANESTA CORP (US) | 1992-06-03 | — | — | EP | claimed |
| WO-1991003099-A1 | COMPRESSED POWDER MEDICAMENTS | ANESTA CORPORATION (US) | 1991-03-07 | — | — | WO | claimed |