SCHEMBL20451990

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2077092	0.89	GSK3B (1.00)	GSK3BCDK4CCND1CCND3CDK6
	SCHEMBL20452096	0.86	CDK4 (0.81)	CDK4CCND1CCND3CDK6CDK9
	SCHEMBL29815412	0.86	CDK4 (0.81)	CDK4CCND1CCND3CDK6CDK9
	SCHEMBL20452142	0.84	CCNA2 (0.59)	GSK3BCDK4CCND1CCND3CDK6
	SCHEMBL29815829	0.83	CDK4 (0.82)	GSK3BCDK4CCND1CCND3CDK6
	SCHEMBL18480846	0.83	CDK4 (0.82)	GSK3BCDK4CCND1CCND3CDK6
	SCHEMBL20451995	0.83	CDK4 (0.82)	CDK4CCND1CCND3CDK6CDK9
	SCHEMBL30777167	0.83	CDK4 (0.82)	CDK4CCND1CCND3CDK6CDK9
	SCHEMBL4168788	0.83	GSK3B (0.88)	GSK3BCDK4CCND1CCND3CDK6
	SCHEMBL20452030	0.82	CDK2 (0.83)	GSK3BCDK4CCND1CCND3CDK6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.