Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 10/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4439679 | 0.88 | HCAR2 (0.56) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL15570481 | 0.88 | HCAR2 (0.56) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL8459101 | 0.85 | HCAR2 (0.50) | HCAR2MAPTMAPK1PRKCA | |
| SCHEMBL871389 | 0.84 | HCAR2 (0.48) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL7037830 | 0.84 | HCAR2 (0.48) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL871387 | 0.84 | HCAR2 (0.48) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL8461078 | 0.84 | HCAR2 (0.51) | HCAR2TSHRMAPTMAPK1 | |
| SCHEMBL9576356 | 0.84 | HCAR2 (0.51) | HCAR2TSHRMAPTMAPK1 | |
| SCHEMBL10837357 | 0.82 | HCAR2 (0.53) | HCAR2TSHRMAPTMAPK1PRKCA | |
| SCHEMBL6049907 | 0.81 | HCAR2 (0.53) | HCAR2TSHRTP53EGLN1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964696-B2 | Chain extenders | POLYNOVO BIOMATERIALS PTY LIMITED (AU) | 2011-06-21 | — | — | US | claimed |
| US-20090175921-A1 | Chain Extenders | POLYNOVO BIOMATERIALS PTY LIMITED | 2009-07-09 | — | — | US | claimed |
| EP-1945690-A1 | CHAIN EXTENDERS | Polynovo Biomaterials Pty Limited (AU) | 2008-07-23 | — | — | EP | claimed |
| WO-2007033418-A1 | CHAIN EXTENDERS | POLYNOVO BIOMATERIALS PTY LIMITED (AU) | 2007-03-29 | — | — | WO | claimed |
| US-20150105530-A1 | CHAIN EXTENDERS | POLYNOVO BIOMATERIALS PTY LTD (AU) | 2015-04-16 | — | — | US | disclosed |
| US-7964696-B2 | Chain extenders | POLYNOVO BIOMATERIALS PTY LIMITED (AU) | 2011-06-21 | — | — | US | disclosed |
| EP-2195361-A1 | HIGH MODULUS POLYURETHANE AND POLYURETHANE/UREA COMPOSITIONS | Polynovo Biomaterials Limited (AU) | 2010-06-16 | — | — | EP | disclosed |
| US-20090175921-A1 | Chain Extenders | POLYNOVO BIOMATERIALS PTY LIMITED | 2009-07-09 | — | — | US | disclosed |
| WO-2009043099-A1 | HIGH MODULUS POLYURETHANE AND POLYURETHANE/UREA COMPOSITIONS | POLYNOVO BIOMATERIALS LIMITED (AU) | 2009-04-09 | — | — | WO | disclosed |
| EP-1945690-A1 | CHAIN EXTENDERS | Polynovo Biomaterials Pty Limited (AU) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007033418-A1 | CHAIN EXTENDERS | POLYNOVO BIOMATERIALS PTY LIMITED (AU) | 2007-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090175921-A1 | Chain Extenders | UMPS, PUF60, SMC1A | HCAR2 2351/4885TSHR 3975/4885TP53 4064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.