SCHEMBL2045574

SCHEMBL2045574

C=C(C)C(=O)OCCCCCC(C)C.C=CC(=O)OCCCCCCCCCCCC

nearest known ligand 0.63

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.63
HPGD P15428 1/20 0.54
ALDH1A1 P00352 2/20 0.50
CYP3A4 P08684 1/20 0.50
HCAR2 Q8TDS4 2/20 0.42
THRB P10828 1/20 0.39
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ATM Q13315 1/20 0.38
NAAA Q02083 1/20 0.37
PLA2G2C Q5R387 1/20 0.36
RAD52 P43351 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
FAAH O00519 1/20 0.36
ABCB1 P08183 1/20 0.36
TP53 P04637 1/20 0.36
HIF1A Q16665 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29110637 1.00 TSHR (0.63) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL31589984 1.00 TSHR (0.63) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL29580127 0.97 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL29581623 0.97 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4HCAR2
Methacrylic Acid SCHEMBL28157465 0.96 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4HCAR2
Acrylic Acid SCHEMBL5613341 0.96 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL29004140 0.95 TSHR (0.56) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL31216393 0.95 TSHR (0.56) TSHRHPGDALDH1A1CYP3A4HCAR2
Acrylic Acid SCHEMBL11171023 0.94 TSHR (0.55) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL11530963 0.92 TSHR (0.52) TSHRHPGDALDH1A1CYP3A4HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114752323-A Acrylate adhesive, adhesive tape and preparation method thereof 江苏皇冠新材料科技有限公司 2022-07-15 CN claimed
CN-114752323-A Acrylate adhesive, adhesive tape and preparation method thereof 江苏皇冠新材料科技有限公司 2022-07-15 CN disclosed
US-8557918-B2 Polymer composites 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-10-15 US disclosed
US-20110144238-A1 POLYMER COMPOSITES 3M INNOVATIVE PROPERTIES COMPANY 2011-06-16 US disclosed
US-7863381-B2 Polymer composites 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-01-04 US disclosed
US-7691932-B2 Method of making a composition and nanocomposites therefrom 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-04-06 US disclosed
US-20100068500-A1 POLYMER COMPOSITES 3M INNOVATIVE PROPERTIES COMPANY 2010-03-18 US disclosed
US-7495051-B2 Nanocomposite and method of making the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-02-24 US disclosed
EP-1991609-A1 POLYMER COMPOSITES 3M Innovative Properties Company (US) 2008-11-19 EP disclosed
WO-2008088619-A1 NANOCOMPOSITE AND METHOD OF MAKING THE SAME 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-07-24 WO disclosed
US-20060189756-A1 POLYMER BLENDS 3M INNOVATIVE PROPERTIES COMPANY 2006-08-24 US disclosed
WO-2006063317-A1 FILLED POLYMER COMPOSITES 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-06-15 WO disclosed
US-20060128870-A1 FILLED POLYMER COMPOSITES 3M INNOVATIVE PROPERTIES COMPANY 2006-06-15 US disclosed
WO-2006055612-A1 MICROSPHERE FILLED POLYMER COMPOSITES 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-05-26 WO disclosed
US-20060105053-A1 Microsphere filled polymer composites 3M INNOVATIVE PROPERTIES COMPANY 2006-05-18 US disclosed
US-20060074167-A1 Method of making a composition and nanocomposites therefrom 3M INNOVATIVE PROPERTIES COMPANY 2006-04-06 US disclosed
US-20060074168-A1 Nanocomposite and method of making the same 3M INNOVATIVE PROPERTIES COMPANY 2006-04-06 US disclosed
WO-2006036390-A1 METHOD OF MAKING A COMPOSITION AND NANOCOMPOSITES THEREFROM 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-04-06 WO disclosed
WO-2006036397-A1 COMPOSITION COMPRISING FLUORINATED BLOCK COPOLYMER INTERCALATED INTO LAYERED SILICATE AND METHOD OF MAKING THE SAME 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-04-06 WO disclosed
US-20060074169-A1 Composition and method of making the same 3M INNOVATIVE PROPERTIES COMPANY 2006-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060105053-A1 Microsphere filled polymer composites PSTPIP2, CD68, PGA5 TSHR 4194/4885HPGD 1588/4885ALDH1A1 3360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.