SCHEMBL20458151

SCHEMBL20458151

CC(C)(C)c1cc(NC(=O)C2CCN2C2CCOCC2)sn1

nearest known ligand 0.58

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 19/20 0.58
CNR1 P21554 10/20 0.58
RPS6KA2 Q15349 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9892818 1.00 CNR2 (0.58) CNR2CNR1RPS6KA2
SCHEMBL9892863 0.79 CNR2 (0.88) CNR2CNR1
SCHEMBL9892794 0.79 CNR2 (0.62) CNR2CNR1
SCHEMBL20458157 0.79 CNR2 (0.88) CNR2CNR1
SCHEMBL9892793 0.78 CNR2 (0.88) CNR2CNR1
SCHEMBL13256791 0.78 CNR2 (0.66) CNR2CNR1
SCHEMBL9892780 0.77 CNR2 (0.56) CNR2CNR1
SCHEMBL9892860 0.76 CNR2 (0.88) CNR2CNR1
SCHEMBL9892902 0.76 CNR2 (0.88) CNR2CNR1
SCHEMBL9892918 0.75 LMNA (0.50) RPS6KA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2443107-B1 AZETIDINE 2 -CARBOXAMIDE DERIVATIVES WHICH MODULATE THE CB2 RECEPTOR BOEHRINGER INGELHEIM INT (DE) 2018-08-08 EP disclosed