Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2123122 | 1.00 | ALDH1A1 (0.60) | ALDH1A1MAPTHSD17B10TSHRHPGD | |
| SCHEMBL9892142 | 0.95 | ALDH1A1 (0.58) | ALDH1A1MAPTHSD17B10TSHRHPGD | |
| SCHEMBL13257045 | 0.94 | ALDH1A1 (0.58) | ALDH1A1MAPTHSD17B10TSHRHPGD | |
| SCHEMBL9892051 | 0.88 | ALDH1A1 (0.54) | ALDH1A1MAPTHSD17B10TSHRHPGD | |
| SCHEMBL9892792 | 0.85 | ALDH1A1 (0.62) | ALDH1A1MAPTHSD17B10TSHRHPGD | |
| SCHEMBL13284776 | 0.81 | ALDH1A1 (0.60) | ALDH1A1MAPTHSD17B10TSHRHPGD | |
| SCHEMBL9892050 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MAPTHSD17B10TSHRHPGD | |
| SCHEMBL16238780 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MAPTHSD17B10ARCNR1 | |
| SCHEMBL16358874 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MAPTHSD17B10TSHRHPGD | |
| SCHEMBL1622016 | 0.75 | ALDH1A1 (0.55) | ALDH1A1MAPTHSD17B10TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443107-B1 | AZETIDINE 2 -CARBOXAMIDE DERIVATIVES WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2018-08-08 | — | — | EP | disclosed |