Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.54 |
| ▸ | DRD2 | P14416 | 6/20 | 0.47 |
| ▸ | DRD3 | P35462 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15947381 | 0.86 | NAMPT (0.58) | NAMPTDRD2DRD3ALDH1A1POLB | |
| SCHEMBL8543987 | 0.84 | NAMPT (0.52) | NAMPTDRD2DRD3MEN1KMT2A | |
| SCHEMBL14853580 | 0.83 | NAMPT (0.55) | NAMPTDRD2DRD3ALDH1A1POLB | |
| SCHEMBL8404673 | 0.83 | DRD3 (0.65) | NAMPTDRD2DRD3ALDH1A1POLB | |
| SCHEMBL8545769 | 0.81 | NAMPT (0.48) | NAMPTDRD2DRD3MEN1KMT2A | |
| SCHEMBL8404672 | 0.80 | NAMPT (0.58) | NAMPTDRD2DRD3MEN1KMT2A | |
| SCHEMBL8543989 | 0.80 | NAMPT (0.49) | NAMPTDRD2DRD3MEN1KMT2A | |
| SCHEMBL15259144 | 0.79 | NAMPT (0.48) | NAMPTDRD2DRD3MEN1KMT2A | |
| SCHEMBL19634722 | 0.78 | NAMPT (0.55) | NAMPTDRD2DRD3MEN1KMT2A | |
| SCHEMBL20458264 | 0.75 | DRD3 (0.50) | NAMPTDRD2DRD3ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2765187-B1 | METHOD FOR PRODUCING MEGAKARYOCYTES AND/OR PLATELETS FROM PLURIPOTENT STEM CELLS | NISSAN CHEMICAL IND LTD (JP) | 2018-08-08 | — | — | EP | disclosed |