Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20458191 | 0.83 | HRH3 (0.52) | HRH3KCNH2KDM4ETP53AR | |
| SCHEMBL2391087 | 0.75 | AR (0.51) | HRH3KCNH2KDM4ETP53AR | |
| SCHEMBL24435216 | 0.74 | AR (0.52) | HRH3KCNH2KDM4ETP53AR | |
| SCHEMBL9891644 | 0.72 | HRH3 (0.46) | HRH3KCNH2KDM4ETP53 | |
| SCHEMBL9892911 | 0.70 | HRH3 (0.53) | HRH3KCNH2KDM4ETP53AR | |
| SCHEMBL9891507 | 0.70 | HRH3 (0.49) | HRH3KCNH2KDM4ETP53 | |
| SCHEMBL1238918 | 0.69 | HRH3 (0.46) | HRH3KCNH2KDM4ETP53 | |
| SCHEMBL3335248 | 0.69 | AR (0.54) | HRH3KCNH2KDM4ETP53AR | |
| SCHEMBL13651291 | 0.68 | ALDH1A1 (0.51) | HRH3KCNH2KDM4ETP53AR | |
| SCHEMBL18787366 | 0.68 | ALDH1A1 (0.51) | HRH3KCNH2KDM4ETP53AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443107-B1 | AZETIDINE 2 -CARBOXAMIDE DERIVATIVES WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2018-08-08 | — | — | EP | disclosed |