Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 8/20 | 0.43 |
| ▸ | PPARG | P37231 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 3/20 | 0.38 |
| ▸ | MPI | P34949 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2045836 | 1.00 | MAPT (0.47) | MAPTKDM4EPPARAPPARGALDH1A1 | |
| SCHEMBL2050856 | 0.91 | MAPT (0.51) | MAPTKDM4EPPARAPPARGALDH1A1 | |
| SCHEMBL2050857 | 0.91 | MAPT (0.51) | MAPTKDM4EPPARAPPARGALDH1A1 | |
| SCHEMBL2044625 | 0.89 | MAPT (0.55) | MAPTKDM4EALDH1A1KMT2APOLB | |
| SCHEMBL2044628 | 0.89 | MAPT (0.55) | MAPTKDM4EALDH1A1KMT2APOLB | |
| SCHEMBL2052834 | 0.87 | KDM4E (0.46) | MAPTKDM4EPPARAPPARGALDH1A1 | |
| SCHEMBL2052836 | 0.87 | KDM4E (0.46) | MAPTKDM4EPPARAPPARGALDH1A1 | |
| SCHEMBL9899206 | 0.86 | HSD11B1 (0.49) | MAPTKDM4EALDH1A1KMT2APOLB | |
| SCHEMBL9899207 | 0.86 | HSD11B1 (0.49) | MAPTKDM4EALDH1A1KMT2APOLB | |
| SCHEMBL2051909 | 0.85 | KDM4E (0.49) | MAPTKDM4EPPARAPPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338544-B2 | Polymers functionalized with polyoxime compounds and methods for their manufacture | BRIDGESTONE CORPORATION (JP) | 2012-12-25 | — | — | US | claimed |
| US-20110152449-A1 | POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2011-06-23 | — | — | US | claimed |
| US-8338544-B2 | Polymers functionalized with polyoxime compounds and methods for their manufacture | BRIDGESTONE CORPORATION (JP) | 2012-12-25 | — | — | US | disclosed |
| US-20110152449-A1 | POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2011-06-23 | — | — | US | disclosed |