Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24574359 | 0.76 | — | — | |
| SCHEMBL2107941 | 0.72 | — | — | |
| SCHEMBL19061149 | 0.71 | LMNA (0.37) | LMNAALDH1A1MCL1MAPT | |
| SCHEMBL2106440 | 0.68 | — | — | |
| SCHEMBL21185421 | 0.67 | — | — | |
| SCHEMBL2612191 | 0.67 | — | — | |
| SCHEMBL6069824 | 0.66 | — | — | |
| SCHEMBL22598066 | 0.65 | — | — | |
| SCHEMBL20326365 | 0.65 | MCL1 (0.34) | LMNAMCL1KMT2A | |
| SCHEMBL12961588 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3357926-A1 | TRANSDERMAL DELIVERY SYSTEMS OF BETA-LACTAM ANTIBIOTICS | Yu, Chongxi (US) | 2018-08-08 | — | — | EP | disclosed |