Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 4/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.36 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26834074 | 0.86 | SLC6A2 (0.42) | SLC6A2PDPK1MTORBCHETACR1 | |
| SCHEMBL20107264 | 0.84 | BCHE (0.43) | SLC6A2PDPK1MTORBCHETACR1 | |
| SCHEMBL20458777 | 0.81 | PDPK1 (0.42) | SLC6A2PDPK1MTORBCHECYP2C19 | |
| SCHEMBL18385931 | 0.79 | SLC6A2 (0.41) | SLC6A2PDPK1MTORBCHETACR1 | |
| SCHEMBL20707960 | 0.78 | CTSL (0.43) | BCHETACR1OPRM1OPRL1CYP2C19 | |
| SCHEMBL18193301 | 0.77 | PDPK1 (0.44) | SLC6A2PDPK1MTORBCHEOPRM1 | |
| SCHEMBL18193304 | 0.77 | PDPK1 (0.44) | SLC6A2PDPK1MTORBCHEOPRM1 | |
| SCHEMBL20234401 | 0.75 | SLC6A2 (0.48) | SLC6A2PDPK1MTORBCHECYP2C19 | |
| SCHEMBL20172483 | 0.75 | SLC6A2 (0.48) | SLC6A2PDPK1MTORBCHECYP2C19 | |
| SCHEMBL20172481 | 0.75 | SLC6A2 (0.48) | SLC6A2PDPK1MTORBCHECYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3357931-A1 | METHODS OF SYNTHESIS OF TRITERPENE PROSAPOGENINS AND TRITERPENE SAPONINS | Sloan Kettering Institute For Cancer Research (US) | 2018-08-08 | — | — | EP | disclosed |