Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 11/20 | 0.47 |
| ▸ | IKZF3 | Q9UKT9 | 10/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.47 |
| ▸ | TNF | P01375 | 5/20 | 0.46 |
| ▸ | IL1B | P01584 | 3/20 | 0.46 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21924058 | 0.87 | CRBN (0.43) | CRBNIKZF3DDB1TNFIL1B | |
| SCHEMBL20459076 | 0.84 | HIF1A (0.39) | CRBNIKZF3DDB1TNFIL1B | |
| SCHEMBL21281357 | 0.82 | CRBN (0.39) | CRBNIKZF3DDB1TNFIL1B | |
| SCHEMBL20459241 | 0.81 | CRBN (0.51) | CRBNIKZF3DDB1TNFIL1B | |
| SCHEMBL17724160 | 0.80 | CRBN (0.71) | CRBNIKZF3DDB1TNFIL1B | |
| SCHEMBL17724106 | 0.80 | CRBN (0.71) | CRBNIKZF3DDB1TNFIL1B | |
| SCHEMBL17724159 | 0.80 | CRBN (0.71) | CRBNIKZF3DDB1TNFIL1B | |
| SCHEMBL19309958 | 0.79 | CRBN (0.43) | CRBNIKZF3DDB1TNFIL1B | |
| SCHEMBL20778899 | 0.78 | CRBN (0.66) | CRBNIKZF3DDB1TNFIL1B | |
| SCHEMBL19514508 | 0.78 | CRBN (0.58) | CRBNIKZF3DDB1TNFIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3357513-A1 | PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Kangpu Biopharmaceuticals, Ltd. (CN) | 2018-08-08 | — | — | EP | disclosed |