Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.39 |
| ▸ | IKZF3 | Q9UKT9 | 10/20 | 0.39 |
| ▸ | TNF | P01375 | 5/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.39 |
| ▸ | IL1B | P01584 | 3/20 | 0.39 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21924058 | 0.88 | CRBN (0.43) | CRBNIKZF3TNFDDB1IL1B | |
| SCHEMBL23470056 | 0.86 | CRBN (0.46) | CRBNIKZF3TNFDDB1IL1B | |
| SCHEMBL21281565 | 0.83 | CRBN (0.59) | CRBNIKZF3TNFDDB1IL1B | |
| SCHEMBL21281543 | 0.83 | BDKRB1 (0.34) | CRBNIKZF3TNFDDB1IL1B | |
| SCHEMBL20459014 | 0.82 | CRBN (0.47) | CRBNIKZF3TNFDDB1IL1B | |
| SCHEMBL21924060 | 0.80 | CRBN (0.46) | CRBNIKZF3TNFDDB1IL1B | |
| SCHEMBL21281545 | 0.80 | CRBN (0.41) | CRBNIKZF3TNFDDB1IL1B | |
| SCHEMBL21281542 | 0.80 | CRBN (0.54) | CRBNIKZF3TNFDDB1IL1B | |
| SCHEMBL19310115 | 0.79 | WDR5 (0.32) | CRBNIKZF3TNFDDB1IL1B | |
| SCHEMBL19309958 | 0.79 | CRBN (0.43) | CRBNIKZF3TNFDDB1IL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3527210-A1 | COMPOSITION, APPLICATION THEREOF AND TREATMENT METHOD | Kangpu Biopharmaceuticals, Ltd. (CN) | 2019-08-21 | — | — | EP | disclosed |