Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 13/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 6/20 | 0.35 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.35 |
| ▸ | CDC7 | O00311 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30951792 | 0.70 | SIRT3 (0.41) | PARP1CDC7 | |
| SCHEMBL23962838 | 0.67 | PARP1 (0.43) | PARP1PARP2PARP3 | |
| SCHEMBL29088228 | 0.64 | PARP1 (0.43) | PARP1DGAT1CES2CES1 | |
| SCHEMBL29851114 | 0.64 | PARP1 (0.43) | PARP1DGAT1CES2CES1 | |
| SCHEMBL17128939 | 0.63 | AURKA (0.58) | PARP1PARP2PARP3 | |
| SCHEMBL477698 | 0.63 | CES2 (0.68) | PARP1DGAT1CES2CES1 | |
| SCHEMBL32669380 | 0.62 | PARP1 (0.47) | PARP1PARP2PARP3CDC7 | |
| SCHEMBL2308943 | 0.62 | CES2 (0.48) | PARP1DGAT1CES2CES1 | |
| SCHEMBL30424329 | 0.62 | CES2 (0.54) | PARP1DGAT1CES2CES1 | |
| SCHEMBL2293368 | 0.62 | PARP1 (0.44) | PARP1PARP2PARP3DGAT1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3357925-A1 | SALT TYPE AND CRYSTAL TYPE OF 4H-PYRAZOLO [1, 5-ALPHA]BENZIMIDAZOLE COMPOUND AND PREPARATION METHOD AND INTERMEDIATE THEREOF | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. (CN) | 2018-08-08 | — | — | EP | disclosed |