Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 7/20 | 0.63 |
| ▸ | HTR6 | P50406 | 12/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16059486 | 0.77 | BRD4 (1.00) | BRD4 | |
| SCHEMBL19574811 | 0.76 | BRD4 (0.52) | BRD4 | |
| SCHEMBL1772003 | 0.73 | BRD4 (0.55) | BRD4HTR6 | |
| SCHEMBL1772423 | 0.68 | BRD4 (0.52) | BRD4HTR6 | |
| SCHEMBL20461458 | 0.67 | BRD4 (0.38) | BRD4HTR6 | |
| SCHEMBL1772540 | 0.66 | HTR6 (0.64) | BRD4HTR6 | |
| SCHEMBL20461344 | 0.66 | BRD4 (0.37) | BRD4HTR6 | |
| SCHEMBL5727247 | 0.62 | HTR6 (0.58) | BRD4HTR6 | |
| SCHEMBL16085698 | 0.61 | BRD4 (1.00) | BRD4 | |
| SCHEMBL16085697 | 0.61 | BRD4 (1.00) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970265-B1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | PLEXXIKON INC (US) | 2018-08-08 | — | — | EP | disclosed |