Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 20/20 | 0.67 |
| ▸ | CRY2 | Q49AN0 | 18/20 | 0.67 |
| ▸ | CRY1 | Q16526 | 13/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20462170 | 0.82 | PER2 (0.69) | PER2CRY2CRY1 | |
| SCHEMBL15380293 | 0.81 | PER2 (1.00) | PER2CRY2CRY1 | |
| SCHEMBL20462131 | 0.78 | PER2 (0.65) | PER2CRY2CRY1 | |
| SCHEMBL20462144 | 0.76 | PER2 (0.65) | PER2CRY2CRY1 | |
| SCHEMBL20462227 | 0.76 | PER2 (0.67) | PER2CRY2CRY1 | |
| SCHEMBL20462289 | 0.74 | PER2 (0.65) | PER2CRY2CRY1 | |
| SCHEMBL20462299 | 0.73 | PER2 (0.67) | PER2CRY2CRY1 | |
| SCHEMBL20462257 | 0.73 | PER2 (0.67) | PER2CRY2CRY1 | |
| SCHEMBL29623020 | 0.73 | PER2 (0.65) | PER2CRY2CRY1 | |
| SCHEMBL15383977 | 0.73 | PER2 (0.69) | PER2CRY2CRY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855458-B1 | CARBAZOLE-CONTAINING SULFONAMIDES AS CRYPTOCHROME MODULATORS | RESET THERAPEUTICS INC (US) | 2018-08-08 | — | — | EP | disclosed |