Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 5/20 | 0.60 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20463309 | 0.86 | HTR2B (0.58) | HTR2BKMT2ASMN1; SMN2POLBMAPT | |
| SCHEMBL20463474 | 0.86 | HTR2B (0.48) | HTR2BKMT2ASMN1; SMN2POLBMAPT | |
| SCHEMBL20463432 | 0.85 | KMT2A (0.62) | HTR2BKMT2AALDH1A1PKM | |
| SCHEMBL20463369 | 0.80 | KMT2A (0.51) | HTR2BKMT2AALDH1A1PKM | |
| SCHEMBL20456432 | 0.80 | KMT2A (0.74) | HTR2BKMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL20463352 | 0.79 | HTR2B (0.62) | HTR2BTRPV1KMT2ASMN1; SMN2POLB | |
| SCHEMBL1299510 | 0.75 | HTR2B (1.00) | HTR2BSMN1; SMN2 | |
| SCHEMBL13873294 | 0.75 | SMN1; SMN2 (0.77) | HTR2BTRPV1SMN1; SMN2POLBMAPT | |
| SCHEMBL7950089 | 0.73 | CARM1 (0.39) | ALDH1A1 | |
| SCHEMBL7945321 | 0.73 | CARM1 (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018144900-A1 | SMALL MOLECULE ANTAGONISTS OF SUMO RELATED MODIFICATION OF CRMP2 AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2018-08-09 | — | — | WO | disclosed |