Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950089 | 1.00 | CARM1 (0.39) | CARM1PRMT6HTR2AEPHX2ALDH1A1 | |
| SCHEMBL7951369 | 0.92 | CARM1 (0.37) | CARM1PRMT6HTR2AEPHX2ALDH1A1 | |
| SCHEMBL7951343 | 0.83 | SLC6A4 (0.46) | HTR2AEPHX2SLC6A4SLC6A3EPHX1 | |
| SCHEMBL21613810 | 0.76 | EPHX2 (0.45) | HTR2AEPHX2MMP13MMP14 | |
| SCHEMBL7961313 | 0.74 | SLC6A4 (0.45) | CARM1PRMT6EPHX2ALDH1A1LIPE | |
| SCHEMBL7950137 | 0.74 | MEN1 (0.40) | CARM1PRMT6ALDH1A1BACE1SLC6A4 | |
| SCHEMBL7949461 | 0.73 | HSD11B1 (0.60) | EPHX2FPR2PROKR1LIPEEPHX1 | |
| SCHEMBL20463333 | 0.73 | HTR2B (0.60) | ALDH1A1 | |
| SCHEMBL14699678 | 0.72 | ALDH1A1 (0.65) | CARM1PRMT6ALDH1A1TSHRBACE1 | |
| SCHEMBL7956021 | 0.72 | CARM1 (0.40) | CARM1PRMT6HTR2AEPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151152-A1 | OXYCARBAMOYL COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2009-12-17 | — | — | WO | disclosed |