SCHEMBL2046367

SCHEMBL2046367

CCCOC(C)OP(=O)(OC(C)OCCC)OC(C)OCCC

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.36
LMNA P02545 1/20 0.32
TSHR P16473 2/20 0.31
TRPM8 Q7Z2W7 1/20 0.31
METAP1 P53582 1/20 0.30
HPGD P15428 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13835928 0.89 CYP3A4 (0.32) CYP3A4
SCHEMBL15283633 0.87 CYP3A4 (0.31) CYP3A4
SCHEMBL37267 0.86 CYP3A4 (0.48) CYP3A4TSHRTRPM8HPGDSMN1; SMN2
SCHEMBL2049552 0.85 CYP3A4 (0.41) CYP3A4TRPM8
SCHEMBL4250513 0.83 LPAR3 (0.44) CYP3A4TRPM8
SCHEMBL2049006 0.83 LPAR3 (0.44) CYP3A4TRPM8
SCHEMBL2048389 0.83 LPAR3 (0.44) CYP3A4TRPM8
SCHEMBL2522276 0.82 METAP1 (0.36) METAP1HSD17B10
SCHEMBL2046370 0.82 SMPD1 (0.42) METAP1HSD17B10
SCHEMBL20213336 0.81 PIK3CD (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2337805-B2 POLYMERIZABLE LIQUID COMPOSITION AND PROCESS FOR THE PRODUCTION OF ORGANIC GLASS STARTING FROM POLYMERIZABLE LIQUID COMPOSITIONS OF THE POLYURETHANE TYPE MITSUI CHEMICALS INC (JP) 2025-06-18 EP disclosed
EP-3129353-B1 METHOD FOR MANUFACTURING XYLYLENE DIISOCYANATES IN THE GASEOUS PHASE COVESTRO DEUTSCHLAND AG (DE) 2024-02-28 EP disclosed
WO-2023106258-A1 POLYMERIZABLE COMPOSITION FOR MANUFACTURING MOLDED ARTICLE, MOLDED ARTICLE AND MANUFACTURING METHOD THEREOF MITSUI CHEMICALS, INC. (JP) 2023-06-15 WO disclosed
CN-106414538-B Composition for producing transparent polythiourethane bodies 科思创德国股份有限公司 2020-02-28 CN disclosed
US-10294198-B2 Method for producing xylylene diisocyanates in the gaseous phase COVESTRO DEUTSCHLAND AG (DE) 2019-05-21 US disclosed
US-10252988-B2 Composition for producing transparent polythiourethane bodies COVESTRO DEUTSCHLAND AG (DE) 2019-04-09 US disclosed
US-20170210702-A1 METHOD FOR PRODUCING XYLYLENE DIISOCYANATES IN THE GASEOUS PHASE COVESTRO DEUTSCHLAND AG (DE) 2017-07-27 US disclosed
US-20170121449-A1 COMPOSITION FOR PRODUCING TRANSPARENT POLYTHIOURETHANE BODIES MITSUI CHEMICALS, INC. (JP) 2017-05-04 US disclosed
US-20170029552-A1 COMPOSITION CONTAINING AROMATIC NITRILES FOR THE PRODUCTION OF TRANSPARENT POLYTHIOURETHANE BODIES COVESTRO DEUTSCHLAND AG (DE) 2017-02-02 US disclosed
EP-2337805-B1 POLYMERIZABLE LIQUID COMPOSITION AND PROCESS FOR THE PRODUCTION OF ORGANIC GLASS STARTING FROM POLYMERIZABLE LIQUID COMPOSITIONS OF THE POLYURETHANE TYPE ACOMON AG (CH) 2014-12-17 EP disclosed
US-8829147-B2 Polymerizable liquid composition and process for the production of organic glass starting from polymerizable liquid compositions of the polyurethane type ACOMON AG (CH) 2014-09-09 US disclosed
EP-2571914-A1 A POLYMERIZATION CATALYST FOR POLYTHIOURETHANES, POLYMERIZABLE LIQUID COMPOSITION AND PROCESS FOR THE PRODUCTION OF ORGANIC POLYTHIOURETHANE GLASS WITH A HIGH REFRACTIVE INDEX Mitsui Chemicals, Inc. (JP) 2013-03-27 EP disclosed
WO-2011144995-A1 A POLYMERIZATION CATALYST FOR POLYTHIOURETHANES, POLYMERIZABLE LIQUID COMPOSITION AND PROCESS FOR THE PRODUCTION OF ORGANIC POLYTHIOURETHANE GLASS WITH A HIGH REFRACTIVE INDEX ACOMON AG (CH) 2011-11-24 WO disclosed
US-20110251301-A1 POLYMERIZABLE LIQUID COMPOSITION AND PROCESS FOR THE PRODUCTION OF ORGANIC GLASS STARTING FROM POLYMERIZABLE LIQUID COMPOSITIONS OF THE POLYURETHANE TYPE ACOMON AG (CH) 2011-10-13 US disclosed
EP-2337805-A1 POLYMERIZABLE LIQUID COMPOSITION AND PROCESS FOR THE PRODUCTION OF ORGANIC GLASS STARTING FROM POLYMERIZABLE LIQUID COMPOSITIONS OF THE POLYURETHANE TYPE ACOMON AG (CH) 2011-06-29 EP disclosed
WO-2010043392-A1 POLYMERIZABLE LIQUID COMPOSITION AND PROCESS FOR THE PRODUCTION OF ORGANIC GLASS STARTING FROM POLYMERIZABLE LIQUID COMPOSITIONS OF THE POLYURETHANE TYPE ACOMON AG (CH) 2010-04-22 WO disclosed
US-4267220-A COMPRISING FIBERS OF A GRAFT POLYMER OR BLEND OF POLYVINYL ALCOHOL AND POLYVINYL CHLORIDE AND A LUBRICANT-OIL DUST ADSORBER DUSKIN FRANCHISE CO., LTD. (JP) 1981-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10252988-B2 Composition for producing transparent polythiourethane bodies PHOSPHO1, PCTP, AGPAT5 CYP3A4 2713/4885LMNA 2055/4885TSHR 2486/4885
US-10294198-B2 Method for producing xylylene diisocyanates in the gaseous phase DCXR, DAD1, PAG1 CYP3A4 715/4885LMNA 2428/4885TSHR 4447/4885
US-20170210702-A1 METHOD FOR PRODUCING XYLYLENE DIISOCYANATES IN THE GASEOUS PHASE DCXR, DAD1, PAG1 CYP3A4 715/4885LMNA 2428/4885TSHR 4447/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.