SCHEMBL20464136

SCHEMBL20464136

CCn1c2ccc(C(=O)c3ccccc3C)cc2c2cc(/C(=N/OC(C)=O)C(=O)CC3CCCC3)ccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.38
KDM4E B2RXH2 3/20 0.38
ALDH1A1 P00352 2/20 0.38
LMNA P02545 2/20 0.38
HPGD P15428 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HTT P42858 2/20 0.37
MAPT P10636 1/20 0.37
RORC P51449 3/20 0.36
RAB9A P51151 1/20 0.36
FFAR1 O14842 1/20 0.36
PTGER4 P35408 7/20 0.36
TUBB4A P04350 1/20 0.34
TUBB P07437 1/20 0.34
TUBA3C P0DPH7 1/20 0.34
TUBA1B P68363 1/20 0.34
TUBA4A P68366 1/20 0.34
TUBB4B P68371 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1721190 1.00 NPC1 (0.38) NPC1KDM4EALDH1A1LMNAHPGD
SCHEMBL1719696 0.99 NPC1 (0.39) NPC1KDM4EALDH1A1LMNAHPGD
SCHEMBL18334615 0.91 KDM4E (0.35) NPC1KDM4EALDH1A1LMNAHPGD
SCHEMBL19632663 0.90 NPC1 (0.39) NPC1KDM4EALDH1A1LMNAHPGD
SCHEMBL28525765 0.89 NPC1 (0.38) NPC1KDM4EALDH1A1LMNAHPGD
SCHEMBL1721191 0.89 KDM4E (0.42) NPC1KDM4EALDH1A1LMNAHPGD
SCHEMBL1720992 0.88 KDM4E (0.41) NPC1KDM4EALDH1A1LMNAHPGD
SCHEMBL21253182 0.85 KMT2A (0.38) NPC1KDM4EALDH1A1LMNAHPGD
SCHEMBL31650942 0.85 KMT2A (0.38) NPC1KDM4EALDH1A1LMNAHPGD
SCHEMBL19632436 0.85 KMT2A (0.38) NPC1KDM4EALDH1A1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12032318-B2 Electrophotographic image forming system with cleaning blade Konica Minolta, Inc. (JP) 2024-07-09 US disclosed
US-12032318-B2 Electrophotographic image forming system with cleaning blade Konica Minolta, Inc. (JP) 2024-07-09 US disclosed
US-20230185227-A1 ELECTROPHOTOGRAPHIC IMAGE FORMING SYSTEM Konica Minolta, Inc. (JP) 2023-06-15 US disclosed
US-20230185227-A1 ELECTROPHOTOGRAPHIC IMAGE FORMING SYSTEM Konica Minolta, Inc. (JP) 2023-06-15 US disclosed
US-10324386-B2 Electrophotographic photoreceptor, image forming apparatus, image forming method, production method of electrophotographic photoreceptor Konica Minolta, Inc. (JP) 2019-06-18 US disclosed
US-20180224761-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, PRODUCTION METHOD OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR Konica Minolta, Inc. (JP) 2018-08-09 US disclosed
US-20180224761-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, PRODUCTION METHOD OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR Konica Minolta, Inc. (JP) 2018-08-09 US disclosed