SCHEMBL1720992

SCHEMBL1720992

CCn1c2ccc(C(=O)c3ccccc3C)cc2c2cc(C(=NO)C(=O)CC3CCCCC3)ccc21

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.41
LMNA P02545 2/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 2/20 0.40
HTT P42858 2/20 0.40
RAB9A P51151 1/20 0.40
NPC1 O15118 1/20 0.40
ALDH1A1 P00352 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
RORC P51449 3/20 0.39
FFAR1 O14842 1/20 0.38
PTGER4 P35408 5/20 0.38
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36
PPARG P37231 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1721191 0.99 KDM4E (0.42) KDM4ELMNAMAPTHPGDHTT
SCHEMBL1719696 0.89 NPC1 (0.39) KDM4ELMNAMAPTHPGDHTT
SCHEMBL20464136 0.88 NPC1 (0.38) KDM4ELMNAMAPTHPGDHTT
SCHEMBL1721190 0.88 NPC1 (0.38) KDM4ELMNAMAPTHPGDHTT
SCHEMBL29501795 0.88 ALDH1A1 (0.42) KDM4ELMNAHPGDHTTRAB9A
SCHEMBL29501794 0.88 ALDH1A1 (0.42) KDM4ELMNAHPGDHTTRAB9A
SCHEMBL852290 0.86 KDM4E (0.42) KDM4ELMNAMAPTHPGDHTT
Acetic Acid SCHEMBL22497416 0.84 KDM4E (0.42) KDM4ELMNAMAPTHPGDHTT
Acetic Acid SCHEMBL29503104 0.84 KDM4E (0.42) KDM4ELMNAMAPTHPGDHTT
SCHEMBL31642410 0.83 KDM4E (0.43) KDM4ELMNAMAPTHPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2407456-B1 CARBAZOLE OXIME ESTER PHOTOINITIATOR CHANGZHOU TRONLY NEW ELECTRONIC MATERIALS CO LTD (CN) 2013-08-28 EP disclosed
EP-2407456-A1 CARBAZOLE OXIME ESTER PHOTOINITIATOR Changzhou Tronly New Electronic Materials Co., Ltd (CN) 2012-01-18 EP disclosed