SCHEMBL20465293

SCHEMBL20465293

c1cc(-c2cc3c4ccccc4n4c5ccccc5c(c2)c34)c2c(c1)ccc1c3ccccc3oc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.42
PRKDC P78527 5/20 0.35
PIK3CD O00329 1/20 0.33
PIK3CB P42338 1/20 0.33
PTGES2 Q9H7Z7 1/20 0.33
GGPS1 O95749 1/20 0.33
ATM Q13315 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CYP19A1 P11511 1/20 0.32
AHR P35869 2/20 0.31
JAK2 O60674 1/20 0.31
ZAP70 P43403 1/20 0.31
SYK P43405 1/20 0.31
ALDH1A1 P00352 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21717852 0.86 ALOX5 (0.52) ALOX5PRKDCPIK3CDPIK3CBPTGES2
SCHEMBL20465301 0.85 ALOX5 (0.39) ALOX5PRKDCPIK3CDPIK3CBPTGES2
SCHEMBL21718080 0.85 ALOX5 (0.43) ALOX5PRKDCPIK3CDPIK3CBPTGES2
SCHEMBL19541050 0.84 ALOX5 (0.50) ALOX5PRKDCPIK3CDPIK3CBPTGES2
SCHEMBL21718042 0.83 ALOX5 (0.45) ALOX5PRKDCPIK3CDPIK3CBPTGES2
SCHEMBL10015165 0.81 ALOX5 (0.51) ALOX5PRKDCPIK3CDPIK3CBPTGES2
SCHEMBL19563861 0.79 ALOX5 (0.48) ALOX5PRKDCPIK3CDPIK3CBPTGES2
SCHEMBL19564038 0.79 ALOX5 (0.44) ALOX5PRKDCPIK3CDPIK3CBPTGES2
SCHEMBL19563937 0.79 ALOX5 (0.44) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL22858282 0.78 ALOX5 (0.48) ALOX5PRKDCPIK3CDPIK3CBPTGES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11512086-B2 Compound for organic electrical element, organic electrical element using compound, and electronic device therefor DUK SAN NEOLUX CO., LTD. (KR) 2022-11-29 US disclosed
US-20180222910-A1 COMPOUND FOR ORGANIC ELECTRICAL ELEMENT, ORGANIC ELECTRICAL ELEMENT USING COMPOUND, AND ELECTRONIC DEVICE THEREFOR DUK SAN NEOLUX CO., LTD. (KR) 2018-08-09 US disclosed
US-20180222910-A1 COMPOUND FOR ORGANIC ELECTRICAL ELEMENT, ORGANIC ELECTRICAL ELEMENT USING COMPOUND, AND ELECTRONIC DEVICE THEREFOR DUK SAN NEOLUX CO., LTD. (KR) 2018-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180222910-A1 COMPOUND FOR ORGANIC ELECTRICAL ELEMENT, ORGANIC ELECTRICAL ELEMENT USING COMPOUND, AND ELECTRONIC DEVICE THEREFOR OR51E2, WEE1, SLC39A11 ALOX5 800/4885PRKDC 4088/4885PIK3CD 3674/4885
US-11512086-B2 Compound for organic electrical element, organic electrical element using compound, and electronic device therefor OR51E2, WEE1, SLC39A11 ALOX5 800/4885PRKDC 4088/4885PIK3CD 3674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.