Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20465925 | 0.90 | SMN1; SMN2 (0.33) | SMN1; SMN2KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL20468292 | 0.84 | ALDH1A1 (0.32) | SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL22280382 | 0.82 | SMN1; SMN2 (0.37) | SMN1; SMN2KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL20465929 | 0.82 | PDE10A (0.32) | — | |
| SCHEMBL24012218 | 0.80 | ALDH1A1 (0.31) | SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL20465984 | 0.76 | ALDH1A1 (0.30) | SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL20465982 | 0.74 | EIF4EBP1 (0.32) | — | |
| SCHEMBL23934171 | 0.74 | PDE10A (0.38) | — | |
| SCHEMBL23934199 | 0.74 | POLB (0.38) | — | |
| SCHEMBL18506154 | 0.73 | SMN1; SMN2 (0.35) | SMN1; SMN2KDM4EALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018141954-A1 | ARYL OR HETEROARYL-SUBSTITUTED IMIDAZO PYRIDINE DERIVATIVES AND THEIR USE AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2018-08-09 | — | — | WO | disclosed |