SCHEMBL2046646

SCHEMBL2046646

CC(=O)ON=C1C=CC=CC1=NOC(C)=O

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
IDO1 P14902 1/20 0.31
TDO2 P48775 1/20 0.31
NSD2 O96028 1/20 0.31
DNMT1 P26358 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9899137 0.87 UCHL3 (0.32) MAPTHTT
SCHEMBL5160353 0.76 MAPT (0.55) MAPTHTT
SCHEMBL2046608 0.75 MIF (0.39) MAPTHTT
SCHEMBL2051065 0.73 UCHL3 (0.32)
SCHEMBL5162076 0.70 MAPT (0.38) MAPTHTT
SCHEMBL5161488 0.68 MIF (0.54) MAPTHTT
SCHEMBL5160864 0.68 MAPT (0.36) MAPTHTT
SCHEMBL3996511 0.67 PLK1 (0.59) MAPTHTT
SCHEMBL3996509 0.67 PLK1 (0.59) MAPTHTT
SCHEMBL13804629 0.67 PLK1 (0.59) MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US claimed
EP-2516475-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-10-31 EP claimed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US claimed
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US disclosed
EP-2516475-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-10-31 EP disclosed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US disclosed