SCHEMBL2046715

SCHEMBL2046715

CCOc1ccc(C(C)(C)C)cc1NC(=O)C(N)=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.56
CYP2C19 P33261 3/20 0.56
CYP2C9 P11712 2/20 0.56
NR1I2 O75469 2/20 0.47
MAPT P10636 2/20 0.47
MAPK1 P28482 2/20 0.47
NPSR1 Q6W5P4 1/20 0.47
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
HTT P42858 1/20 0.45
TP53 P04637 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
KDM4E B2RXH2 1/20 0.44
NPC1 O15118 1/20 0.44
MITF O75030 1/20 0.44
THRB P10828 1/20 0.44
RAB9A P51151 1/20 0.44
HDAC1 Q13547 2/20 0.44
HDAC8 Q9BY41 2/20 0.44
HDAC6 Q9UBN7 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29788633 1.00 CYP1A2 (0.56) CYP1A2CYP2C19CYP2C9NR1I2MAPT
SCHEMBL9502725 0.88 CYP1A2 (0.55) CYP1A2CYP2C19CYP2C9NR1I2MAPT
SCHEMBL10585826 0.87 CYP2C19 (0.48) CYP1A2CYP2C19CYP2C9NR1I2MAPT
SCHEMBL27547614 0.86 NR1I2 (0.51) NR1I2MAPTMAPK1NPSR1SMN1; SMN2
SCHEMBL27564662 0.86 NR1I2 (0.51) NR1I2MAPTMAPK1NPSR1SMN1; SMN2
SCHEMBL30105372 0.84 CYP1A2 (0.54) CYP1A2CYP2C19CYP2C9NR1I2MAPT
SCHEMBL7949549 0.84 CYP1A2 (0.54) CYP1A2CYP2C19CYP2C9NR1I2MAPT
SCHEMBL29365745 0.82 CYP2C19 (0.52) CYP1A2CYP2C19CYP2C9NR1I2MAPT
SCHEMBL30298079 0.82 CYP2C19 (0.52) CYP1A2CYP2C19CYP2C9NR1I2MAPT
SCHEMBL208693 0.82 CYP2C19 (0.52) CYP1A2CYP2C19CYP2C9NR1I2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3330317-B1 POLYACETAL RESIN COMPOSITION AND POLYACETAL RESIN MOLDED ARTICLE MITSUBISHI ENG PLASTICS CORP (JP) 2021-10-06 EP disclosed
CN-107614605-B Polyacetal resin composition and polyacetal resin molded article 三菱工程塑料株式会社 2021-02-19 CN disclosed
EP-3330317-A1 POLYACETAL RESIN COMPOSITION AND POLYACETAL RESIN MOLDED ARTICLE Mitsubishi Engineering-Plastics Corporation (JP) 2018-06-06 EP disclosed
EP-2330155-B1 POLYACETAL RESIN COMPOSITION, RESIN MOLDED ARTICLE, AND METHOD AND AGENT FOR IMPROVING POLYACETAL RESIN RAW MATERIAL COMPOSITION MITSUBISHI ENG PLASTICS CORP (JP) 2016-08-24 EP disclosed
US-8846788-B2 Polyacetal resin composition, resin molded article, and method and agent for improving polyacetal resin raw material composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2014-09-30 US disclosed
US-20110230602-A1 POLYACETAL RESIN COMPOSITION, RESIN MOLDED ARTICLE, AND METHOD AND AGENT FOR IMPROVING POLYACETAL RESIN RAW MATERIAL COMPOSITION MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2011-09-22 US disclosed
EP-2330155-A1 POLYACETAL RESIN COMPOSITION, RESIN MOLDED ARTICLE, AND METHOD AND AGENT FOR IMPROVING POLYACETAL RESIN RAW MATERIAL COMPOSITION Mitsubishi Engineering-Plastics Corporation (JP) 2011-06-08 EP disclosed
EP-0624624-B1 Polyacetal resin composition MITSUBISHI GAS CHEMICAL CO (JP) 1998-03-11 EP disclosed
US-5432216-A Polyacetal resin composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1995-07-11 US disclosed
EP-0624624-A1 Polyacetal resin composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1994-11-17 EP disclosed