SCHEMBL7949549

SCHEMBL7949549

CCOc1ccc(C(C)(C)C)cc1NC(=O)C(=O)Nc1ccc(C(C)(C)C)cc1CC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.54
CYP2C19 P33261 3/20 0.54
CYP2C9 P11712 2/20 0.54
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
HTT P42858 1/20 0.46
NR1I2 O75469 1/20 0.46
MAPT P10636 3/20 0.45
NPSR1 Q6W5P4 2/20 0.45
MAPK1 P28482 1/20 0.45
TP53 P04637 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HDAC1 Q13547 2/20 0.43
HDAC8 Q9BY41 2/20 0.43
HDAC6 Q9UBN7 2/20 0.43
RXFP1 Q9HBX9 1/20 0.42
ALDH1A1 P00352 3/20 0.42
CYP3A4 P08684 2/20 0.41
POLB P06746 1/20 0.41
EPHX1 P07099 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30105372 1.00 CYP1A2 (0.54) CYP1A2CYP2C19CYP2C9MEN1KMT2A
SCHEMBL30182959 0.90 CYP2C19 (0.52) CYP1A2CYP2C19CYP2C9MEN1KMT2A
SCHEMBL29365745 0.90 CYP2C19 (0.52) CYP1A2CYP2C19CYP2C9MEN1KMT2A
SCHEMBL30298079 0.90 CYP2C19 (0.52) CYP1A2CYP2C19CYP2C9MEN1KMT2A
SCHEMBL208693 0.90 CYP2C19 (0.52) CYP1A2CYP2C19CYP2C9MEN1KMT2A
SCHEMBL9502725 0.86 CYP1A2 (0.55) CYP1A2CYP2C19CYP2C9MEN1KMT2A
SCHEMBL29788633 0.84 CYP1A2 (0.56) CYP1A2CYP2C19CYP2C9MEN1KMT2A
SCHEMBL2046715 0.84 CYP1A2 (0.56) CYP1A2CYP2C19CYP2C9MEN1KMT2A
SCHEMBL14080278 0.81 SMN1; SMN2 (0.51) CYP1A2CYP2C19CYP2C9MEN1KMT2A
SCHEMBL14274490 0.80 CYP1A2 (0.50) CYP1A2CYP2C19CYP2C9MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3997165-B1 STABILIZER COMPOSITION FOR SILYL-MODIFIED POLYMER SEALANTS CLARIANT INT LTD (CH) 2023-09-06 EP disclosed
WO-2021005201-A1 STABILIZER COMPOSITION FOR SILYL-MODIFIED POLYMER SEALANTS CLARIANT PLASTICS & COATINGS LTD (CH) 2021-01-14 WO disclosed
CN-107922587-B Curable composition and optical element using same 株式会社大赛璐 2020-12-25 CN disclosed
US-10829586-B2 Curable composition and optical element obtained using same DAECEL CORPORATION (JP) 2020-11-10 US disclosed
US-20200115491-A1 CURABLE COMPOSITION AND OPTICAL ELEMENT OBTAINED USING SAME DAICEL CORPORATION (JP) 2020-04-16 US disclosed
US-10584200-B2 Curable composition and optical element obtained using same DAICEL CORPORATION (JP) 2020-03-10 US disclosed
US-10550219-B2 2020-02-04 US disclosed
EP-3333210-A1 CURABLE COMPOSITION AND OPTICAL ELEMENT USING SAME Daicel Corporation (JP) 2018-06-13 EP disclosed
US-6296674-B1 Candle wax stabilized with red-shift benzotriazoles CIBA SPECIALTY CHEMICALS CORPORATION 2001-10-02 US disclosed
WO-2001057125-A1 CANDLE WAX STABILIZED WITH RED-SHIFTED BENZOTRIAZOLES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-08-09 WO disclosed